Pulmonary Cryptococcus Infection After Mono-Chemotherapy With Gemcitabine.

Mono-chemotherapy with gemcitabine (difluorodeoxycytidine) is an effective cancer chemotherapy, and is often used instead of a more effective but more toxic combination chemotherapy regimen. Infection associated with gemcitabine is very rare. We present a case of Cryptococcus neoformans pneumonia th...

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Detalles Bibliográficos
Publicado en:Respiratory Care Vol. 56; no. 3; pp. 330 - 333
Autores principales: Yu-Guang Chen, Te-Yu Lin, Gen-Min Lin, Jung-Chung Lin
Formato: case study diagnostic images pictorial Journal Article
Publicado: Mary Ann Liebert, Inc. Mar2011
Acceso en línea:Ver este registro en EBSCOhost
Descripción
Sumario:Mono-chemotherapy with gemcitabine (difluorodeoxycytidine) is an effective cancer chemotherapy, and is often used instead of a more effective but more toxic combination chemotherapy regimen. Infection associated with gemcitabine is very rare. We present a case of Cryptococcus neoformans pneumonia that developed after 5 courses of gemcitabine for advanced bladder carcinoma. Lung biopsy and antigens demonstrated C. neoformans. The pneumonia resolved after antifungal therapy.