Assessment of Performance and Reliability of Computer-Aided Detection Scheme Using Content-Based Image Retrieval Approach and Limited Reference Database.

Content-based image retrieval approach was used in our computer-aided detection (CAD) schemes for breast cancer detection with mammography. In this study, we assessed CAD performance and reliability using a reference database including 1500 positive (breast mass) regions of interest (ROIs) and1500 n...

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Publicado en:Journal of Digital Imaging Vol. 24; no. 2; pp. 352 - 360
Autores principales: Wang, Xiao, Park, Sang, Zheng, Bin
Formato: research tables/charts Journal Article
Publicado: Springer Nature Apr2011
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2011
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      pub: Springer Nature
      place: New York, New York
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        atl: Assessment of Performance and Reliability of Computer-Aided Detection Scheme Using Content-Based Image Retrieval Approach and Limited Reference Database.
      aug:
        au:
          Wang, Xiao
          Park, Sang
          Zheng, Bin
        affil: Department of Radiology, University of Pittsburgh, 3362 Fifth Avenue Pittsburgh 15213 USA
      sug:
        subj:
          Image Retrieval Methods
          Breast Neoplasms Diagnosis
          Brain Diseases Diagnosis
          Diagnosis, Computer Assisted
          Human
          ROC Curve
          Radiographic Image Enhancement
          Algorithms
          Retrospective Design
          Digitizers
          Validation Studies
          P-Value
          Funding Source
      ab: Content-based image retrieval approach was used in our computer-aided detection (CAD) schemes for breast cancer detection with mammography. In this study, we assessed CAD performance and reliability using a reference database including 1500 positive (breast mass) regions of interest (ROIs) and1500 normal ROIs. To test the relationship between CAD performance and the similarity level between the queried ROI and the retrieved ROIs, we applied a set of similarity thresholds to the retrieved similar ROIs selected by the CADschemes for all queried suspicious regions, and used only the ROIs that were above the threshold for assessing CAD performance at each threshold level. Using the leave-one-out testing method, we computed areas under receiver operating characteristic (ROC) curves ( A) to assess CAD performance. The experimental results showed that as threshold increase, (1) less true positive ROIs can be referenced in the database than normal ROIs and (2) the A value was monotonically increased from 0.854±0.004 to 0.932±0.016. This study suggests that (1) in order to more accurately detect and diagnose subtle masses, a large and diverse database is required, and (2) assessing the reliability of the decision scores based on the similarity measurement is important in application of the CBIR-based CAD schemes when the limited database is used.
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    language: English
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