Helicobacter pylori in the oral cavity and gastric mucosa: a meta-analysis.
J Oral Pathol Med (2011) 40: 317-324 Background: Helicobacter pylori have been found in the oral cavity and stomach. This study is to establish whether there might be any associations between isolates of H. pylori in the oral cavity and those in the stomach by meta-analysis. Methods: Studies reporti...
| Publicado en: | Journal of Oral Pathology & Medicine Vol. 40; no. 4; pp. 317 - 325 |
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| Autores principales: | , |
| Formato: | research Journal Article |
| Publicado: |
Wiley-Blackwell
Apr2011
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104853868&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104853868 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09042512 8E8 jtl: Journal of Oral Pathology & Medicine issn: 09042512 maglogo: Y pubinfo: dt: Apr2011 vid: 40 iid: 4 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 104853868 2010989586 10.1111/j.1600-0714.2011.01006.x NLM21294774 104853868 ppf: 317 ppct: 8 formats: tig: atl: Helicobacter pylori in the oral cavity and gastric mucosa: a meta-analysis. aug: au: Zou QH Li RQ affil: Department of Microbiology, Peking University Health Science Center, Beijing, China Beijing Center for Disease Control and Prevention, Beijing, China. sug: subj: Gastric Mucosa Microbiology Helicobacter Pylori Mouth Microbiology Mouth Mucosa Microbiology Helicobacter Infections Human Odds Ratio ab: J Oral Pathol Med (2011) 40: 317-324 Background: Helicobacter pylori have been found in the oral cavity and stomach. This study is to establish whether there might be any associations between isolates of H. pylori in the oral cavity and those in the stomach by meta-analysis. Methods: Studies reporting raw data on the prevalence of H. pylori infection in the oral cavity in gastric H. pylori-positive and H. pylori-negative patients, in patients with gastroesophageal diseases, and in healthy individuals and studies reporting data on the eradication rate in the oral cavity or stomach, published in the English language, were identified through MEDLINE and EMBASE up to May 2010. Results: The prevalence of H. pylori infection in the oral cavity in gastric H. pylori-positive patients was significantly higher (45.0%) than that in gastric H. pylori-negative patients (23.9%). The pooled odds ration (OR) was 3.61 and the 95% CI was 1.91-6.82 (P < 0.0001). Different diagnostic methods produced different pooled ORs with PCR the highest (OR = 5.11, 95% CI: 2.08-12.54, P = 0.0004) and rapid urease test (RUT) the lowest (OR = 2.00, 95% CI: 0.80-5.00, P = 0.14). The 44.8% (91/203) prevalence of H. pylori infection in the oral cavity in patients with clinical and/or histological gastroesophageal diseases was significantly higher than the 13.2% (21/159) in patients with non-ulcerous dyspepsia or healthy controls (OR = 5.15, 95% CI: 2.97-8.92, P < 0.00001). The eradication efficiency in stomach is 85.8% (187/218), while in oral cavity it is only 5.7% (9/158). The OR is 55.59, P < 0.00001. Conclusions: There is a close relation between the infection of H. pylori in the oral cavity and stomach. H. pylori in the oral cavity are more difficult to be eradicated than in the stomach. It may be a source of reinfection. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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