Characteristics and effects of nurse dosing over-rides on computer-based intensive insulin therapy protocol performance.

Objective: To determine characteristics and effects of nurse dosing over-rides of a clinical decision support system (CDSS) for intensive insulin therapy (IIT) in critical care units.Design: Retrospective analysis of patient database records and ethnographic study of nurses using IIT CDSS.Measuremen...

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Publicado en:Journal of the American Medical Informatics Association Vol. 18; no. 3; pp. 251 - 259
Autores principales: Campion TR Jr, May AK, Waitman LR, Ozdas A, Lorenzi NM, Gadd CS, Campion, Thomas R Jr, May, Addison K, Waitman, Lemuel R, Ozdas, Asli, Lorenzi, Nancy M, Gadd, Cynthia S
Formato: research Journal Article
Publicado: Oxford University Press / USA May2011
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Oxford University Press / USA
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        atl: Characteristics and effects of nurse dosing over-rides on computer-based intensive insulin therapy protocol performance.
      aug:
        au:
          Campion TR Jr
          May AK
          Waitman LR
          Ozdas A
          Lorenzi NM
          Gadd CS
          Campion, Thomas R Jr
          May, Addison K
          Waitman, Lemuel R
          Ozdas, Asli
          Lorenzi, Nancy M
          Gadd, Cynthia S
        affil: Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
      sug:
        subj:
          Decision Support Systems, Clinical
          Dosage Forms
          Drug Therapy, Computer Assisted
          Insulin Administration and Dosage
          Nursing Practice
          Adult
          Attitude to Computers
          Female
          Guideline Adherence
          Hypoglycemia Prevention and Control
          Intensive Care Units
          Male
          Middle Age
          Retrospective Design
          Tennessee
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Objective: To determine characteristics and effects of nurse dosing over-rides of a clinical decision support system (CDSS) for intensive insulin therapy (IIT) in critical care units.Design: Retrospective analysis of patient database records and ethnographic study of nurses using IIT CDSS.Measurements: The authors determined the frequency, direction-greater than recommended (GTR) and less than recommended (LTR)- and magnitude of over-rides, and then compared recommended and over-ride doses' blood glucose (BG) variability and insulin resistance, two measures of IIT CDSS associated with mortality. The authors hypothesized that rates of hypoglycemia and hyperglycemia would be greater for recommended than over-ride doses. Finally, the authors observed and interviewed nurse users.Results: 5.1% (9075) of 179,452 IIT CDSS doses were over-rides. 83.4% of over-ride doses were LTR, and 45.5% of these were ≥ 50% lower than recommended. In contrast, 78.9% of GTR doses were ≤ 25% higher than recommended. When recommended doses were administered, the rate of hypoglycemia was higher than the rate for GTR (p = 0.257) and LTR (p = 0.033) doses. When recommended doses were administered, the rate of hyperglycemia was lower than the rate for GTR (p = 0.003) and LTR (p < 0.001) doses. Estimates of patients' insulin requirements were higher for LTR doses than recommended and GTR doses. Nurses reported trusting IIT CDSS overall but appeared concerned about recommendations when administering LTR doses.Conclusion: When over-riding IIT CDSS recommendations, nurses overwhelmingly administered LTR doses, which emphasized prevention of hypoglycemia but interfered with hyperglycemia control, especially when BG was >150 mg/dl. Nurses appeared to consider the amount of a recommended insulin dose, not a patient's trend of insulin resistance, when administering LTR doses overall. Over-rides affected IIT CDSS protocol performance.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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