Can Myocardial Strain Differentiate Hypertrophic from Infiltrative Etiology of a Thickened Septum?
Objectives: Radial systolic strain (ɛ) assessed by echocardiography has been shown to identify patterns of normal septal motion brought about by different layers, including left ventricular (LV) subendocardial (LV subendo) and mural (LV mural) layers. We aimed to use myocardial strain in assessing r...
| Publicado en: | Echocardiography Vol. 28; no. 4; pp. 408 - 416 |
|---|---|
| Autores principales: | , , , , , |
| Formato: | diagnostic images research tables/charts tracings Journal Article |
| Publicado: |
Wiley-Blackwell
Apr2011
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104876271&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104876271 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 07422822 GSE jtl: Echocardiography issn: 07422822 maglogo: Y pubinfo: dt: Apr2011 vid: 28 iid: 4 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 104876271 60093118 10.1111/j.1540-8175.2010.01344.x NLM21323993 104876271 ppf: 408 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Can Myocardial Strain Differentiate Hypertrophic from Infiltrative Etiology of a Thickened Septum? aug: au: Engvall, Christer Henein, Michael Holmgren, Anders Suhr, Ole B. Mörner, Stellan Lindqvist, Per affil: Department of Clinical Physiology sug: subj: Heart Septum Pathology Heart Septum Ultrasonography Myocardial Diseases Etiology Myocardial Diseases Ultrasonography Echocardiography Methods Human Descriptive Statistics Middle Age Aged Male Female Academic Medical Centers Sweden Data Analysis Software Unpaired T-Tests One-Way Analysis of Variance Paired T-Tests Heart Ventricle, Left Physiopathology Heart Ventricle, Left Ultrasonography Funding Source Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Objectives: Radial systolic strain (ɛ) assessed by echocardiography has been shown to identify patterns of normal septal motion brought about by different layers, including left ventricular (LV) subendocardial (LV subendo) and mural (LV mural) layers. We aimed to use myocardial strain in assessing radial and longitudinal myocardial function in normal and thickened septum and to test if myocardial strain can differentiate hypertrophic from infiltrative cause of thickened septum. Methods: Forty-five patients (age 61 ± 13 years, 22 males), 13 with hypertrophic cardiomyopathy, 15 with aortic stenosis, and 17 with familial amyloid polyneuropathy, were studied and compared with 29 controls (age 61 ± 12 years, 17 males) using 1D strain and conventional echocardiography. Results: Patients had normal LV ejection fraction and stroke volume but heart rate was higher (P < 0.05) compared to controls. Septal ɛ was reduced (-7.6 ± 7.0% vs. -14.0 ± 5.5%, for LV mural and -7.9 ± 14.7% vs. -20.3 ±-7.9% for LV subendo, P < 0.001 for both layers) across LV longitudinal axis but not along its radial axis. No difference was found in any of ɛ measurements between patient groups. A decrease in strain length by 50% increased the septal strain by more than 60% in both radial and longitudinal axes. Conclusion: Septal systolic strain measurements showed reduced longitudinal function but its localized nature failed to demonstrate radial disturbances in patients with pathologically thickened septum. No difference was found in systolic strain between patients according to the etiology of septal thickness. This limitation might be either technical or is explained by the maintained radial function in all patient groups. (Echocardiography 2011;28:408-415) pubtype: Academic Journal doctype: diagnostic images research tables/charts tracings Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|