Can galactography-guided stereotactic, 11-gauge, vacuum-assisted breast biopsy of intraductal lesions serve as an alternative to surgical biopsy?
The purpose of this study was to determine the value of galactography-guided, stereotactic, vacuum-assisted breast biopsy (VABB) for the assessment of intraductal breast lesions and its potential as a therapeutic tool that could eliminate the need for surgical excision. Eighteen patients (median age...
| Publicado en: | European Radiology Vol. 19; no. 12; pp. 2878 - 2886 |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Dec2009
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104878043&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104878043 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Dec2009 vid: 19 iid: 12 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104878043 45235139 NLM19565246 2011018158 10.1007/s00330-009-1502-7 NLM19565246 104878043 ppf: 2878 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Can galactography-guided stereotactic, 11-gauge, vacuum-assisted breast biopsy of intraductal lesions serve as an alternative to surgical biopsy? aug: au: Reiner CS Helbich TH Rudas M Ponhold L Riedl CC Kropf N Fuchsjäger MH Reiner, Caecilia S Helbich, Thomas H Rudas, Margaretha Ponhold, Lothar Riedl, Christopher C Kropf, Nina Fuchsjäger, Michael H affil: Department of Radiology, Medical University of Vienna, Austria sug: subj: Biopsy, Needle Methods Breast Neoplasms Diagnosis Carcinoma, Ductal, Breast Diagnosis Breast Pathology Mammography Methods Stereotaxic Techniques Therapy, Computer Assisted Methods Adult Aged Aged, 80 and Over Breast Neoplasms Surgery Carcinoma, Ductal, Breast Surgery Female Human Middle Age Reproducibility of Results Sensitivity and Specificity Adult: 19-44 years Aged: 65+ years Aged, 80 & over Middle Aged: 45-64 years Female ab: The purpose of this study was to determine the value of galactography-guided, stereotactic, vacuum-assisted breast biopsy (VABB) for the assessment of intraductal breast lesions and its potential as a therapeutic tool that could eliminate the need for surgical excision. Eighteen patients (median age 64 years, range 37-80) with nipple discharge and galactography-verified intraductal lesions underwent galactography-guided, stereotactic, 11-gauge VABB followed by surgery. Histopathology findings from VABB and subsequent surgery were compared. Underestimation and false-negative rates were assessed. After VABB, histopathology revealed invasive ductal carcinoma (IDC) in three (17%), ductal carcinoma in situ (DCIS) in six (33%), high-risk lesions in six (33%) and benign lesions in three (17%) cases. After surgical biopsy, histopathology confirmed the previously established diagnosis in 11 lesions (61%). The underestimation rate for high-risk lesions and DCIS was 50% (6/12). The false-negative rate was 7% (1/14). Histopathology examination after surgery showed that not a single lesion had been completely removed at VABB. Galactography-guided VABB is a feasible diagnostic tool. However, its value as a therapeutic procedure is limited because of the high number of underestimated and missed lesions and because of the histopathological detection of lesions' remnants in every case. Surgical excision should be the therapeutic gold standard in cases of pathological nipple discharge and galactography abnormalities. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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