Follow-up cervical length in asymptomatic high-risk women and the risk of spontaneous preterm birth.
Objective:To determine whether further cervical length shortening by transvaginal ultrasonography in asymptomatic high-risk women with a short cervical length adds additional predictive value for spontaneous preterm birth and perinatal morbidity.Study Design:Women with a history of spontaneous prete...
| Publicado en: | Journal of Perinatology Vol. 31; no. 5; pp. 318 - 324 |
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| Autores principales: | , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
May2011
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104882202&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104882202 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 07438346 DZF jtl: Journal of Perinatology issn: 07438346 maglogo: Y pubinfo: dt: May2011 vid: 31 iid: 5 pid: 2579 pub: Springer Nature place: Dordrecht, <Blank> artinfo: ui: 104882202 60243756 10.1038/jp.2010.149 NLM21183925 104882202 ppf: 318 ppct: 6 formats: fmt: @attributes: type: P tig: atl: Follow-up cervical length in asymptomatic high-risk women and the risk of spontaneous preterm birth. aug: au: Crane, J M G Hutchens, D affil: Department of Obstetrics and Gynecology, Eastern Health, Memorial University, St John's, Newfoundland, Canada sug: subj: Childbirth, Premature Risk Factors Cervix Physiology Weights and Measures Human Female Pregnancy Ultrasonography Methods Perinatal Death Risk Factors Conization Uterus Abnormalities Retrospective Design Prospective Studies Newfoundland and Labrador ROC Curve Data Analysis Software T-Tests Chi Square Test Fisher's Exact Test Mann-Whitney U Test Adult Descriptive Statistics Adult: 19-44 years Female ab: Objective:To determine whether further cervical length shortening by transvaginal ultrasonography in asymptomatic high-risk women with a short cervical length adds additional predictive value for spontaneous preterm birth and perinatal morbidity.Study Design:Women with a history of spontaneous preterm birth, loop electrosurgical excision procedure, cone biopsy or uterine anomaly, who were pregnant with singleton gestations and were found by transvaginal ultrasonography to have a cervical length <3.0 cm at 20 to 28 weeks' gestation, and who underwent a follow-up cervical length within 3 weeks were evaluated, comparing those with further cervical length shortening (>10%) to those without further shortening. Primary outcomes were spontaneous preterm birth <35 weeks' gestation and perinatal morbidity. Secondary outcomes included spontaneous preterm birth <37 weeks, <34 weeks, <32 weeks, birth weight <2500 g, maternal and other neonatal outcomes.Result:Compared with women without further cervical shortening, those with further shortening were found by univariate analyses to have higher rates of spontaneous preterm birth <35 weeks (34.8 versus 8.5%, P=0.014), <37 weeks (56.5 versus 21.3%, P=0.003), <34 weeks (30.4 versus 2.1%, P=0.001), <32 weeks (21.7 versus 0%, P=0.003), birth weight <2500 g (60.9 versus 17.0%, P<0.0001), neonatal intensive care unit admission (47.8 versus 17.0%, P=0.006) and composite perinatal morbidity (43.5 versus 14.9%, P=0.009). Logistic regression revealed the only independent predictors of spontaneous preterm birth <35 weeks were further cervical length shortening (adjusted odds ratio (aOR) 5.73; 95% confidence interval (CI) 1.31 to 24.43) and gestational age at short cervical length (aOR 0.95; 95% CI 0.91 to 0.99).Conclusion:Further cervical length shortening in asymptomatic high-risk women with a short cervical length is an important independent predictor of spontaneous preterm birth <35 weeks and perinatal morbidity. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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