Exposing misclassified HIV/AIDS deaths in South Africa.

Objective To quantify the deaths from human immunodeficiency virus (HIV) infection or acquired immunodeficiency syndrome (AIDS) that are misattributed to other causes in South Africa's death registration data and to adjust for this bias. Methods Deaths in the World Health Organization's mortality da...

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Publicado en:Bulletin of the World Health Organization Vol. 89; no. 4; pp. 278 - 286
Autores principales: Birnbaum, Jeanette Kurian, Murray, Christopher J. L., Lozano, Rafael
Formato: research tables/charts Journal Article
Publicado: World Health Organization Apr2011
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Exposing misclassified HIV/AIDS deaths in South Africa.
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          Birnbaum, Jeanette Kurian
          Murray, Christopher J. L.
          Lozano, Rafael
        affil: Institute for Health Metrics and Evaluation, University of Washington, 2301 5th Avenue (Suite 600), Seattle, WA, 98121, United States of America.
      sug:
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          Acquired Immunodeficiency Syndrome Mortality
          Mortality Classification
          Funding Source
          Human
          South Africa
          Adult
          Middle Age
          Male
          Female
          Adolescence
          Infant, Newborn
          Infant
          Child, Preschool
          Child
          Aged
          Aged, 80 and Over
          Age Factors
          Sex Factors
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Adolescent: 13-18 years
          Infant, Newborn: birth-1 month
          Infant: 1-23 months
          Child, Preschool: 2-5 years
          Child: 6-12 years
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Objective To quantify the deaths from human immunodeficiency virus (HIV) infection or acquired immunodeficiency syndrome (AIDS) that are misattributed to other causes in South Africa's death registration data and to adjust for this bias. Methods Deaths in the World Health Organization's mortality database were distributed among 48 mutually exclusive causes. For each cause, age- and sex-specific global death rates were compared with the average rate among people aged 65-69, 70-74 and 75-79 years to generate "relative" global death rates. Relative rates were also computed for South Africa alone. Differences between global and South African relative death rates were used to identify the causes to which deaths from HIV/AIDS were misattributed in South Africa and quantify the HIV/AIDS deaths misattributed to each. These deaths were then reattributed to HIV/AIDS. Findings In South Africa, deaths from HIV/AIDS are often misclassified as being caused by 14 other conditions. Whereas in 1996-2006 deaths attributed to HIV/AIDS accounted for 2.0-2.5% of all registered deaths in South Africa, our analysis shows that the true cause-specific mortality fraction rose from 19% (uncertainty range: 7-28%) to 48% (uncertainty range: 38-50%) over that period. More than 90% of HIV/AIDS deaths were found to have been misattributed to other causes during 1996-2006. Conclusion Adjusting for cause of death misclassification, a simple procedure that can be carried out in any country, can improve death registration data and provide empirical estimates of HIV/AIDS deaths that may be useful in assessing estimates from demographic models.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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