Borderline breast lesions: comparison of malignancy underestimation rates with 14-gauge core needle biopsy versus 11-gauge vacuum-assisted device.

Objective: To compare malignancy underestimation rates in the case of percutaneous diagnosis of borderline breast lesions(B3) at 14-g core-needle-biopsy (CNB) and at 11-g vacuum-assisted-biopsy (VAB).Methods: The histological results of 4764 image-guided breast biopsies were retrospectively reviewed...

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Publicado en:European Radiology Vol. 21; no. 6; pp. 1200 - 1207
Autores principales: Londero V, Zuiani C, Linda A, Battigelli L, Brondani G, Bazzocchi M, Londero, Viviana, Zuiani, Chiara, Linda, Anna, Battigelli, Luisa, Brondani, Giovanni, Bazzocchi, Massimo
Formato: research Journal Article
Publicado: Springer Nature Jun2011
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2011
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      pub: Springer Nature
      place: New York, New York
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        2011040864
        10.1007/s00330-010-2053-7
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        atl: Borderline breast lesions: comparison of malignancy underestimation rates with 14-gauge core needle biopsy versus 11-gauge vacuum-assisted device.
      aug:
        au:
          Londero V
          Zuiani C
          Linda A
          Battigelli L
          Brondani G
          Bazzocchi M
          Londero, Viviana
          Zuiani, Chiara
          Linda, Anna
          Battigelli, Luisa
          Brondani, Giovanni
          Bazzocchi, Massimo
        affil: Institute of Radiology, University of Udine, Azienda Ospedaliero Universitaria di Udine, P.le S.Maria della Misericordia, 33100, Udine, Italy
      sug:
        subj:
          Biopsy, Needle Equipment and Supplies
          Breast Neoplasms Pathology
          Needles
          Ultrasonography Methods
          Adult
          Aged
          Aged, 80 and Over
          Biopsy
          Breast Neoplasms Ultrasonography
          Equipment Failure
          False Negative Results
          Female
          Middle Age
          Reproducibility of Results
          Sensitivity and Specificity
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
          Female
      ab: Objective: To compare malignancy underestimation rates in the case of percutaneous diagnosis of borderline breast lesions(B3) at 14-g core-needle-biopsy (CNB) and at 11-g vacuum-assisted-biopsy (VAB).Methods: The histological results of 4764 image-guided breast biopsies were retrospectively reviewed. 300 B3, 151 benign papillomas, 88 radial sclerosing lesions, 46 lobular neoplasia, 15 atypical ductal hyperplasia diagnosed at ultrasound-guided 14-g CNB (76%) or stereotactically-guided 11-g VAB (24%) were identified. On average, 5 cores were obtained with CNB and 12 with VAB. Biopsy variables were reviewed and correlated with surgical excision or follow-up (>24 months). Lesion- and device-specific underestimation rates of malignancy were calculated.Results: Surgical excision was performed on 237 lesions: 178 were benign, 21 atypical, 38 cancers. The remaining 63 lesions were unchanged at follow-up. Overall malignancy underestimation rate was 12.7% at 14-g CNB and 12.5% at 11-g VAB. Based on excision histology or follow-up, lesion-specific underestimation rates were: benign papillomas: 14-g CNB 11%, 11-g VAB 0%; RSL: 14-g CNB 6%, 11-g VAB 4%; LN: 14-g CNB 40%, 11-g VAB 23%; ADH: 14-g CNB 33%; 11-g VAB 22%.Conclusion: In the case of percutaneous diagnosis of B3 lesions, underestimation of malignancy occurs regardless of the biopsy method.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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