Tractography of lumbar nerve roots: initial results.

Objectives: The aims of this preliminary study were to demonstrate the feasibility of in vivo diffusion tensor imaging (DTI) and fibre tracking (FT) of the lumbar nerve roots, and to assess potential differences in the DTI parameters of the lumbar nerves between healthy volunteers and patients suffe...

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Published in:European Radiology Vol. 21; no. 6; pp. 1153 - 1160
Main Authors: Balbi V, Budzik JF, Duhamel A, Bera-Louville A, Le Thuc V, Cotten A, Balbi, Vincent, Budzik, Jean-François, Duhamel, Alain, Bera-Louville, Anne, Le Thuc, Vianney, Cotten, Anne
Format: research Journal Article
Published: Springer Nature Jun2011
Online Access:View this record in EBSCOhost
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      dt: Jun2011
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      pub: Springer Nature
      place: New York, New York
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        2011040868
        10.1007/s00330-010-2049-3
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        atl: Tractography of lumbar nerve roots: initial results.
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          Balbi V
          Budzik JF
          Duhamel A
          Bera-Louville A
          Le Thuc V
          Cotten A
          Balbi, Vincent
          Budzik, Jean-François
          Duhamel, Alain
          Bera-Louville, Anne
          Le Thuc, Vianney
          Cotten, Anne
        affil: Service de Radiologie et d'Imagerie musculo-squelettique, Hôpital Roger Salengro, CHRU de Lille Rue Emile Laine, 59037, Lille Cedex, France
      sug:
        subj:
          Magnetic Resonance Imaging Methods
          Intervertebral Disk Displacement Pathology
          Lumbar Vertebrae Pathology
          Radiculopathy Pathology
          Spinal Nerve Roots Pathology
          Pilot Studies
          Female
          Human
          Intervertebral Disk Displacement Complications
          Male
          Radiculopathy Etiology
          Reproducibility of Results
          Sensitivity and Specificity
          Female
          Male
      ab: Objectives: The aims of this preliminary study were to demonstrate the feasibility of in vivo diffusion tensor imaging (DTI) and fibre tracking (FT) of the lumbar nerve roots, and to assess potential differences in the DTI parameters of the lumbar nerves between healthy volunteers and patients suffering from disc herniation.Methods: Nineteen patients with unilateral sciatica related to posterolateral or foraminal disc herniation and 19 healthy volunteers were enrolled in this study. DTI with tractography of the L5 or S1 nerves was performed. Mean fractional anisotropy (FA) and mean diffusivity (MD) values were calculated from tractography images.Results: FA and MD values could be obtained from DTI-FT images in all controls and patients. The mean FA value of the compressed lumbar nerve roots was significantly lower than the FA of the contralateral nerve roots (p = 0.0001) and of the nerve roots of volunteers (p = 0.0001). MD was significantly higher in compressed nerve roots than in the contralateral nerve root (p = 0.0002) and in the nerve roots of volunteers (p = 0.04).Conclusion: DTI with tractography of the lumbar nerves is possible. Significant changes in diffusion parameters were found in the compressed lumbar nerves.
      pubtype: Academic Journal
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        research
        Journal Article
      ougenre: Article
    language: English
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