Modelling the atypical absorption of menatetrenone and the metabolism to its epoxide: effect of VKORC1 polymorphism.

This study aimed to model the atypical absorption of menatetrenone and its epoxide metabolite and to examine the influence of the single nucleotide polymorphism (SNP) of vitamin K2 epoxide reductase complex subunit 1 (VKORC1) on the pharmacokinetics. After the administration of 30 mg of menatetrenon...

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Bibliographic Details

Published in:	Journal of Clinical Pharmacy & Therapeutics Vol. 36; no. 3; pp. 390 - 399
Main Authors:	Baek, I. H., Kang, W., Yun, H. Y., Lee, S. S., Kwon, K. I.
Format:	equations & formulas pictorial research tables/charts Journal Article
Published:	Wiley-Blackwell Jun2011
Online Access:	View this record in EBSCOhost