Sensitivity and Specificity of a CAD Solution for Lung Nodule Detection on Chest Radiograph with CTA Correlation.
The objective of this research was to determine the sensitivity and specificity of a commercially available computer-aided detection (CAD) system for detection of lung nodule on posterior-anterior (PA) chest radiograph in a varied patient population who are referred to computed tomographic angiogram...
| Publicado en: | Journal of Digital Imaging Vol. 24; no. 3; pp. 405 - 411 |
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| Autores principales: | , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Springer Nature
Jun2011
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104894854&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104894854 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 08971889 DOQ jtl: Journal of Digital Imaging issn: 08971889 maglogo: N pubinfo: dt: Jun2011 vid: 24 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104894854 60502982 10.1007/s10278-010-9284-7 NLM20354756 104894854 ppf: 405 ppct: 6 formats: fmt: @attributes: type: P tig: atl: Sensitivity and Specificity of a CAD Solution for Lung Nodule Detection on Chest Radiograph with CTA Correlation. aug: au: Moore, William Ripton-Snyder, Jennifer Wu, George Hendler, Craig affil: Stony Brook University Hospital, 100 Nicolls Road, HSC Level IV, Room 120 Stony Brook 11733 USA sug: subj: Diagnosis, Computer Assisted Radiography, Thoracic Lung Radiography Lung Neoplasms Diagnosis Lung Neoplasms Radiography Human Sensitivity and Specificity Angiography Spearman's Rank Correlation Coefficient Predictive Value of Tests Data Analysis Software Adolescence Adult Middle Age Aged Aged, 80 and Over Female Male Retrospective Design Confidence Intervals Lung Pathology Adolescent: 13-18 years Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Female Male ab: The objective of this research was to determine the sensitivity and specificity of a commercially available computer-aided detection (CAD) system for detection of lung nodule on posterior-anterior (PA) chest radiograph in a varied patient population who are referred to computed tomographic angiogram (CTA) of the chest as a reference standard. Patients who had a PA chest radiograph with concomitant CTA of the chest were included in this retrospective study. The PA chest radiograph was analyzed by a CAD device, and results were recorded. A qualitative assessment of the CAD results was performed using a 5-point Likert scale. The CTA was then reviewed to determine if there were correlative nodules. The presence of a correlative nodule between 0.5 cm and 1.5 cm was considered a positive result. The baseline sensitivity of the system was determined to be 0.707 (95% CI = 0.52-0.86), with a specificity of 0.50 (95% CI = 0.38-0.76). Positive predictive value was 0.30 (95% CI = 0.24-0.49), with a negative predictive value of 0.858 (95% CI = 0.82-0.95), and accuracy of 0.555 (95% CI = 0.40-0.66). When excluding nodules that were qualitatively determined by a thoracic radiologist to be false positives, the specificity was 0.781 (95% CI = 0.764-0.839), the positive predictive value was 0.564 (95% CI = 0.491-0.654), the negative predictive value was 0.829 (95% CI = 0.819-0.878), and the accuracy was 0.737 (95% CI = 0.721-0.801). The use of CAD for lung nodule detection on chest radiograph, when used in conjunction with an experienced radiologist, has a very good sensitivity, specificity, and accuracy. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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