Baseline Dependency of Minimal Clinically Important Improvement.

Background. Minimal clinically important improvement (MCII) is the smallest outcome measure change important to patients. Research suggests that MCII is dependent on patients' baseline functional status measures. Objective. The purposes of this study were: (1) to confirm whether MCII is dependent on...

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Publicado en:Physical Therapy Vol. 91; no. 5; pp. 675 - 689
Autores principales: Wang, Ying-Chih, Hart, Dennis L., Stratford, Paul W., Mioduski, Jerome E.
Formato: research tables/charts Journal Article
Publicado: Oxford University Press / USA May2011
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Oxford University Press / USA
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          Wang, Ying-Chih
          Hart, Dennis L.
          Stratford, Paul W.
          Mioduski, Jerome E.
        affil: Assistant Professor, Department of Occupational Science and Technology, University of Wisconsin--Milwaukee, Milwaukee, Wisconsin; Senior Data Analyst, Focus On Therapeutic Outcomes, Inc, Knoxville, Tennessee; Adjunct Faculty, Department of Physical Medicine and Rehabilitation, Feinberg School of Medicine, Northwestern University, Chicago, Illinois
      sug:
        subj:
          Outcome Assessment
          Functional Status
          Knee Joint Pathology
          Musculoskeletal Diseases Physiopathology
          Measurement Issues and Assessments
          Human
          Prospective Studies
          Demography
          Scales
          Summated Rating Scaling
          Secondary Analysis
          Nonexperimental Studies
          Computerized Adaptive Testing
          International Classification of Functioning, Disability, and Health
          Effect Size
          ROC Curve
          Confidence Intervals
          Adult
          Middle Age
          Sensitivity and Specificity
          Female
          Male
          P-Value
          Clinical Assessment Tools
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Background. Minimal clinically important improvement (MCII) is the smallest outcome measure change important to patients. Research suggests that MCII is dependent on patients' baseline functional status measures. Objective. The purposes of this study were: (1) to confirm whether MCII is dependent on patients' admission scores and (2) to test whether MCII is dependent on selected demographic characteristics. Study Design and Setting. This was a prospective, longitudinal, observational cohort study of 6,651 patients with orthopedic knee impairments treated in 332 outpatient rehabilitation clinics in 27 states in the United States. Outcome Measures. Patient self-reports of functional status (FS) from the Lower Extremity Functional Scale were assessed using a computerized adaptive testing application (0-100 scale). Methods. An anchored-based longitudinal method, with a 15-point Likert-type scale (-7 to +7), was used to provide a global rating of change (GROC). The MCII threshold for the GROC was defined at a cut-score of +3 or greater and was determined using nonparametric receiver operating characteristic curve analysis for each of the following variables: sex, symptom acuity, age group, and quartile of baseline FS scores. Results. The results showed that MCII was dependent on patient baseline and demographic characteristics. Patients who were male, were younger, had more-acute symptoms, or had lower FS scores at admission required more FS change to report meaningful change. Limitations. As this study was a secondary analysis, how the length of treatment mediated the relationship between the independent and dependent variables was unclear. Conclusions. Although a single MCII index may provide a standard cut-score defining the smallest FS change that is meaningful to patients, researchers and clinicians should be aware that MCII is context specific and not a fixed attribute. Current results may help researchers, clinicians, and policy makers to interpret FS change related to the importance of the change to the patient.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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