Cardiac anisotropy in boundary-element models for the electrocardiogram.

The boundary-element method (BEM) is widely used for electrocardiogram (ECG) simulation. Its major disadvantage is its perceived inability to deal with the anisotropic electric conductivity of the myocardial interstitium, which led researchers to represent only intracellular anisotropy or neglect an...

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Publicado en:Medical & Biological Engineering & Computing Vol. 47; no. 7; pp. 719 - 730
Autores principales: Potse M, Dubé B, Vinet A, Potse, Mark, Dubé, Bruno, Vinet, Alain
Formato: pictorial research tables/charts Journal Article
Publicado: Springer Nature Jul2009
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
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        atl: Cardiac anisotropy in boundary-element models for the electrocardiogram.
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        au:
          Potse M
          Dubé B
          Vinet A
          Potse, Mark
          Dubé, Bruno
          Vinet, Alain
        affil: Research Center, Sacré-Coeur Hospital, 5400 Boulevard Gouin Ouest, Montreal, QC, H4J 1C5, Canada
      sug:
        subj:
          Electrocardiography
          Models, Biological Methods
          Comparative Studies
          Human
      ab: The boundary-element method (BEM) is widely used for electrocardiogram (ECG) simulation. Its major disadvantage is its perceived inability to deal with the anisotropic electric conductivity of the myocardial interstitium, which led researchers to represent only intracellular anisotropy or neglect anisotropy altogether. We computed ECGs with a BEM model based on dipole sources that accounted for a "compound" anisotropy ratio. The ECGs were compared with those computed by a finite-difference model, in which intracellular and interstitial anisotropy could be represented without compromise. For a given set of conductivities, we always found a compound anisotropy value that led to acceptable differences between BEM and finite-difference results. In contrast, a fully isotropic model produced unacceptably large differences. A model that accounted only for intracellular anisotropy showed intermediate performance. We conclude that using a compound anisotropy ratio allows BEM-based ECG models to more accurately represent both anisotropies.
      pubtype: Academic Journal
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        research
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    language: English
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