Automatic noise-level detection for extra-cellular micro-electrode recordings.

Extra-cellular neuro-recording signals used for functional mapping in deep brain stimulation (DBS) surgery and invasive brain computer interfaces, may suffer from poor signal to noise ratio. Therefore, a reliable automatic noise estimate is essential to extract spikes from recordings. We show that c...

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Publicado en:Medical & Biological Engineering & Computing Vol. 47; no. 7; pp. 791 - 801
Autores principales: Dolan K, Martens HC, Schuurman PR, Bour LJ, Dolan, Kevin, Martens, H C F, Schuurman, P R, Bour, L J
Formato: research Journal Article
Publicado: Springer Nature Jul2009
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2009
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s11517-009-0494-4
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        atl: Automatic noise-level detection for extra-cellular micro-electrode recordings.
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          Dolan K
          Martens HC
          Schuurman PR
          Bour LJ
          Dolan, Kevin
          Martens, H C F
          Schuurman, P R
          Bour, L J
        affil: Philips Research, High Tech Campus 34, 5656 AE, Eindhoven, The Netherlands
      sug:
        subj:
          Artifacts
          Brain Mapping
          Electric Stimulation
          Electrophysiology Methods
          Parkinson Disease Therapy
          Signal Processing, Computer Assisted
      ab: Extra-cellular neuro-recording signals used for functional mapping in deep brain stimulation (DBS) surgery and invasive brain computer interfaces, may suffer from poor signal to noise ratio. Therefore, a reliable automatic noise estimate is essential to extract spikes from recordings. We show that current methods are biased toward overestimation of noise-levels with increasing neuronal activity or artifacts. An improved and novel method is proposed that is based on an estimate of the mode of the distribution of the signal envelope. Our method makes use of the inherent characteristics of the noise distribution. For band-limited Gaussian noise the envelope of the signal is known to follow the Rayleigh distribution. The location of the peak of this distribution provides a reliable noise-level estimate. It is demonstrated that this new 'envelope' method gives superior performance both on simulated data, and on actual micro-electrode recordings made during the implantation surgery of DBS electrodes for the treatment of Parkinson's disease.
      pubtype: Academic Journal
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        research
        Journal Article
      ougenre: Article
    language: English
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