Dynamics of pulsatile flow in fractal models of vascular branching networks.
Efficient regulation of blood flow is critically important to the normal function of many organs, especially the brain. To investigate the circulation of blood in complex, multi-branching vascular networks, a computer model consisting of a virtual fractal model of the vasculature and a mathematical...
| Publicado en: | Medical & Biological Engineering & Computing Vol. 47; no. 7; pp. 763 - 773 |
|---|---|
| Autores principales: | , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Jul2009
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104906643&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104906643 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01400118 PO0 jtl: Medical & Biological Engineering & Computing issn: 01400118 maglogo: N pubinfo: dt: Jul2009 vid: 47 iid: 7 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104906643 NLM19468774 2010304527 10.1007/s11517-009-0492-6 NLM19468774 104906643 ppf: 763 ppct: 10 formats: fmt: @attributes: type: P tig: atl: Dynamics of pulsatile flow in fractal models of vascular branching networks. aug: au: Bui A Sutalo ID Manasseh R Liffman K Bui, Anh Sutalo, Ilija D Manasseh, Richard Liffman, Kurt affil: Division of Materials Science and Engineering, Commonwealth Scientific and Industrial Research Organisation (CSIRO), PO Box 56, Highett, VIC, 3190, Australia sug: subj: Cerebrovascular Circulation Computer Simulation Models, Biological Human ab: Efficient regulation of blood flow is critically important to the normal function of many organs, especially the brain. To investigate the circulation of blood in complex, multi-branching vascular networks, a computer model consisting of a virtual fractal model of the vasculature and a mathematical model describing the transport of blood has been developed. Although limited by some constraints, in particular, the use of simplistic, uniformly distributed model for cerebral vasculature and the omission of anastomosis, the proposed computer model was found to provide insights into blood circulation in the cerebral vascular branching network plus the physiological and pathological factors which may affect its functionality. The numerical study conducted on a model of the middle cerebral artery region signified the important effects of vessel compliance, blood viscosity variation as a function of the blood hematocrit, and flow velocity profile on the distributions of flow and pressure in the vascular network. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|