Value of diffusion-weighted imaging to detect small malignant pelvic lymph nodes at 3 T.

Objective: To investigate the usefulness of diffusion-weighted imaging (DWI) to discriminate between metastatic and non-metastatic small lymph nodes in pelvic carcinoma.Materials and Methods: A total of 259 patients (180 normal, 79 metastatic) prospectively underwent DWI at 3 T. We measured the shor...

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Publicado en:European Radiology Vol. 20; no. 8; pp. 1803 - 1812
Autores principales: Roy C, Bierry G, Matau A, Bazille G, Pasquali R, Roy, Catherine, Bierry, Guillaume, Matau, Andrea, Bazille, Gauthier, Pasquali, Rémy
Formato: research Journal Article
Publicado: Springer Nature Aug2010
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2010
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      pub: Springer Nature
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        atl: Value of diffusion-weighted imaging to detect small malignant pelvic lymph nodes at 3 T.
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          Roy C
          Bierry G
          Matau A
          Bazille G
          Pasquali R
          Roy, Catherine
          Bierry, Guillaume
          Matau, Andrea
          Bazille, Gauthier
          Pasquali, Rémy
        affil: Department of Radiology B, Universitary Hospital of Strasbourg, Strasbourg, France
      sug:
        subj:
          Magnetic Resonance Imaging Methods
          Lymph Nodes Pathology
          Pelvic Neoplasms Diagnosis
          Pelvic Neoplasms
          Adult
          Aged
          Female
          Human
          Neoplasm Metastasis
          Male
          Middle Age
          Reproducibility of Results
          Sensitivity and Specificity
          Adult: 19-44 years
          Aged: 65+ years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Objective: To investigate the usefulness of diffusion-weighted imaging (DWI) to discriminate between metastatic and non-metastatic small lymph nodes in pelvic carcinoma.Materials and Methods: A total of 259 patients (180 normal, 79 metastatic) prospectively underwent DWI at 3 T. We measured the short-axis diameter and the mean apparent diffusion coefficient (ADC) value. Lymph nodes with a short-axis diameter larger than 8 mm were recorded as being suspected metastatic lymph nodes. Imaging data were correlated station by station with histopathological results.Results: A total of 140 metastatic nodes were accurately matched with histology. On T2w, the short-axis diameter for non-metastatic and metastatic lymph nodes was 6.4 mm +/- 2.5 mm and 8.3 mm +/- 4.5 mm, respectively. Almost all metastatic or non-metastatic nodes had similar high signal intensity on DWI (except in 5 cases) with a homogeneous pattern. The mean ADC values (10(-3) mm(3)/s +/- standard deviation) of involved lymph nodes, control iliac nodes and control inguinal nodes were 924 +/- 217, 968 +/- 182 and 1,036 +/- 181, respectively. There were no statistically significant differences in the ADC of metastatic and non-metastatic nodes.Conclusion: Isolated measurement of mean ADC values in a suspected station does not contribute to the diagnosis of metastatic nodes, in patients with small ambiguous nodes.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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