Lung nodule volumetry: segmentation algorithms within the same software package cannot be used interchangeably.
Objective: We examined the reproducibility of lung nodule volumetry software that offers three different volumetry algorithms.Methods: In a lung cancer screening trial, 188 baseline nodules >5 mm were identified. Including follow-ups, these nodules formed a study-set of 545 nodules. Nodules were ind...
| Publicado en: | European Radiology Vol. 20; no. 8; pp. 1878 - 1886 |
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| Autores principales: | , , , , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Aug2010
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104912171&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104912171 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Aug2010 vid: 20 iid: 8 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104912171 51989451 NLM20306082 2010709993 10.1007/s00330-010-1749-z NLM20306082 PMC2899012 104912171 ppf: 1878 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Lung nodule volumetry: segmentation algorithms within the same software package cannot be used interchangeably. aug: au: Ashraf H de Hoop B Shaker SB Dirksen A Bach KS Hansen H Prokop M Pedersen JH Ashraf, H de Hoop, B Shaker, S B Dirksen, A Bach, K S Hansen, H Prokop, M Pedersen, J H affil: Department of Radiology, Gentofte Hospital, Copenhagen University, Hellerup, Denmark sug: subj: Algorithms Image Interpretation, Computer Assisted Methods Lung Neoplasms Radiography Software Tomography, X-Ray Computed Methods Aged Female Human Male Middle Age Reproducibility of Results Sensitivity and Specificity Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Objective: We examined the reproducibility of lung nodule volumetry software that offers three different volumetry algorithms.Methods: In a lung cancer screening trial, 188 baseline nodules >5 mm were identified. Including follow-ups, these nodules formed a study-set of 545 nodules. Nodules were independently double read by two readers using commercially available volumetry software. The software offers readers three different analysing algorithms. We compared the inter-observer variability of nodule volumetry when the readers used the same and different algorithms.Results: Both readers were able to correctly segment and measure 72% of nodules. In 80% of these cases, the readers chose the same algorithm. When readers used the same algorithm, exactly the same volume was measured in 50% of readings and a difference of >25% was observed in 4%. When the readers used different algorithms, 83% of measurements showed a difference of >25%.Conclusion: Modern volumetric software failed to correctly segment a high number of screen detected nodules. While choosing a different algorithm can yield better segmentation of a lung nodule, reproducibility of volumetric measurements deteriorates substantially when different algorithms were used. It is crucial even in the same software package to choose identical parameters for follow-up. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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