Electronic cleansing for CT colonography: does it help CAD software performance in a high-risk population for colorectal cancer?

Objective: To compare the performance of computer-aided detection (CAD) for CT colonography (CTC) with and without electronic cleansing (EC) in a high-risk population tagged with a faecal tagging (FT) protocol.Methods: Thirty-two patients underwent CTC followed by same-day colonoscopy. All patients...

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Published in:European Radiology Vol. 20; no. 8; pp. 1905 - 1917
Main Authors: Wi JY, Kim SH, Lee JY, Kim SG, Han JK, Choi BI, Wi, Jae Yeon, Kim, Se Hyung, Lee, Jae Young, Kim, Sang Gyun, Han, Joon Koo, Choi, Byung Ihn
Format: research Journal Article
Published: Springer Nature Aug2010
Online Access:View this record in EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: Electronic cleansing for CT colonography: does it help CAD software performance in a high-risk population for colorectal cancer?
      aug:
        au:
          Wi JY
          Kim SH
          Lee JY
          Kim SG
          Han JK
          Choi BI
          Wi, Jae Yeon
          Kim, Se Hyung
          Lee, Jae Young
          Kim, Sang Gyun
          Han, Joon Koo
          Choi, Byung Ihn
        affil: Department of Radiology, Seoul National University College of Medicine, Seoul, Korea
      sug:
        subj:
          Colonography, Computed Tomographic Methods
          Colorectal Neoplasms Radiography
          Feces
          Growth Substances Diagnostic Use
          Information Science Methods
          Radiographic Image Enhancement Methods
          Subtraction Technique
          Algorithms
          Contrast Media
          Female
          Human
          Male
          Radiographic Image Interpretation, Computer-Assisted Methods
          Reproducibility of Results
          Risk Factors
          Sensitivity and Specificity
          Female
          Male
      ab: Objective: To compare the performance of computer-aided detection (CAD) for CT colonography (CTC) with and without electronic cleansing (EC) in a high-risk population tagged with a faecal tagging (FT) protocol.Methods: Thirty-two patients underwent CTC followed by same-day colonoscopy. All patients underwent bowel preparation and FT with barium and gastrografin. Each CTC dataset was processed with colon CAD with and without EC. Per-polyp sensitivity was calculated. The average number of false-positive (FP) results and their causes were also analysed and compared.Results: Eighty-six polyps were detected in 29 patients. Per-polyp sensitivities of CAD with EC (93.8% and 100%) were higher than those without EC (84.4% and 87.5%) for polyps >or=6 mm and >or=10 mm, respectively. However, the differences were not significant. The average number (6.3) of FPs of CAD with EC was significantly larger than that (3.1) without EC. The distribution of FPs in both CAD settings was also significantly different. The most common cause of FPs was the ileocaecal valve in both datasets. However, untagged faeces was a significantly less common cause of FPs with EC, EC-related artefacts being more common.Conclusion: Electronic cleansing has the potential to improve per-polyp sensitivity of CTC CAD, although the significantly larger number of FPs with EC remains to be improved.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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