Chronic mitral regurgitation detected on cardiac MDCT: differentiation between functional and valvular aetiologies.

Objective: To determine whether cardiac computed tomography (MDCT) can differentiate between functional and valvular aetiologies of chronic mitral regurgitation (MR) compared with echocardiography (TTE).Methods: Twenty-seven patients with functional or valvular MR diagnosed by TTE and 19 controls pr...

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Publicado en:European Radiology Vol. 20; no. 8; pp. 1886 - 1896
Autores principales: Killeen RP, Arnous S, Martos R, Abbara S, Quinn M, Dodd JD, Killeen, Ronan P, Arnous, Samer, Martos, Ramon, Abbara, Suhny, Quinn, Martin, Dodd, Jonathan D
Formato: research Journal Article
Publicado: Springer Nature Aug2010
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2010
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      pub: Springer Nature
      place: New York, New York
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        atl: Chronic mitral regurgitation detected on cardiac MDCT: differentiation between functional and valvular aetiologies.
      aug:
        au:
          Killeen RP
          Arnous S
          Martos R
          Abbara S
          Quinn M
          Dodd JD
          Killeen, Ronan P
          Arnous, Samer
          Martos, Ramon
          Abbara, Suhny
          Quinn, Martin
          Dodd, Jonathan D
        affil: Department of Radiology, St. Vincent's University Hospital, Dublin, Ireland
      sug:
        subj:
          Mitral Valve Insufficiency Etiology
          Mitral Valve Insufficiency Radiography
          Tomography, X-Ray Computed Methods
          Ventricular Dysfunction, Left Complications
          Ventricular Dysfunction, Left Radiography
          Aged
          Aged, 80 and Over
          Chronic Disease
          Diagnosis, Differential
          Echocardiography
          Female
          Human
          Male
          Middle Age
          Mitral Valve Insufficiency Classification
          Mitral Valve Insufficiency Ultrasonography
          Reproducibility of Results
          Sensitivity and Specificity
          Ventricular Dysfunction, Left Ultrasonography
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
          Female
          Male
      ab: Objective: To determine whether cardiac computed tomography (MDCT) can differentiate between functional and valvular aetiologies of chronic mitral regurgitation (MR) compared with echocardiography (TTE).Methods: Twenty-seven patients with functional or valvular MR diagnosed by TTE and 19 controls prospectively underwent cardiac MDCT. The morphological appearance of the mitral valve (MV) leaflets, MV geometry, MV leaflet angle, left ventricular (LV) sphericity and global/regional wall motion were analysed. The coronary arteries were evaluated for obstructive atherosclerosis.Results: All control and MR cases were correctly identified by MDCT. Significant differences were detected between valvular and control groups for anterior leaflet length (30 +/- 7 mm vs. 22 +/- 4 mm, P < 0.02) and thickness (3.0 +/- 1 mm vs. 2.2 +/- 1 mm, P < 0.01). High-grade coronary stenosis was detected in all patients with functional MR compared with no controls (P < 0.001). Significant differences in those with/without MV prolapse were detected in MV tent area (-1.0 +/- 0.6 mm vs. 1.3 +/- 0.9 mm, P < 0.0001) and MV tent height (-0.7 +/- 0.3 mm vs. 0.8 +/- 0.8 mm, P < 0.0001). Posterior leaflet angle was significantly greater for functional MR (37.9 +/- 19.1 degrees vs. 22.9 +/- 14 degrees , P < 0.018) and less for valvular MR (0.6 +/- 35.5 degrees vs. 22.9 +/- 14 degrees, P < 0.017). Sensitivity, specificity, and positive and negative predictive values of MDCT were 100%, 95%, 96% and 100%.Conclusion: Cardiac MDCT allows the differentiation between functional and valvular causes of MR.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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