Transient elastography with a new probe for obese patients for non-invasive staging of non-alcoholic steatohepatitis.
Objective: Transient elastography (TE) has shown promising results for the staging of liver fibrosis in patients with non-alcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH) with the limitation that 25% of obese patients cannot be examined with the standard TE probe. The aim of this stu...
| Publicado en: | European Radiology Vol. 20; no. 10; pp. 2390 - 2397 |
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| Autores principales: | , , , , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Oct2010
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104924006&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104924006 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Oct2010 vid: 20 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104924006 53703839 NLM20526777 2010796854 10.1007/s00330-010-1820-9 NLM20526777 104924006 ppf: 2390 ppct: 7 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Transient elastography with a new probe for obese patients for non-invasive staging of non-alcoholic steatohepatitis. aug: au: Friedrich-Rust M Hadji-Hosseini H Kriener S Herrmann E Sircar I Kau A Zeuzem S Bojunga J Friedrich-Rust, Mireen Hadji-Hosseini, Hassan Kriener, Susanne Herrmann, Eva Sircar, Ishani Kau, Annika Zeuzem, Stefan Bojunga, Joerg affil: Department of Internal Medicine 1, Johann Wolfgang Goethe-University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany sug: subj: Ultrasonography Methods Fatty Liver Complications Fatty Liver Diagnosis Obesity Complications Adult Aged Biopsy Diagnostic Imaging Female Fibrosis Human Liver Pathology Male Middle Age ROC Curve Reproducibility of Results Sensitivity and Specificity Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Objective: Transient elastography (TE) has shown promising results for the staging of liver fibrosis in patients with non-alcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH) with the limitation that 25% of obese patients cannot be examined with the standard TE probe. The aim of this study was to evaluate a new XL probe for obese patients for the staging of liver fibrosis in NAFLD/NASH.Methods: Fifty patients with NAFLD/NASH and histological assessment of liver fibrosis were included in the study. All patients received TE with the standard probe (M probe) and the new XL probe, and the results were compared with liver histology.Results: The diagnostic accuracy expressed as the area under the ROC curve for TE measurements with the M probe and the XL probe was 0.80 and 0.82 for the diagnosis of significant fibrosis, and 0.91 and 0.95 for the diagnosis of liver cirrhosis, respectively. Eighty-three percent of the patients who could not be measured with the M probe could be measured using the XL probe.Conclusion: Transient elastography using the XL probe for obese patients can be performed with comparable diagnostic accuracy to the standard probe and enables the examination of significantly more obese patients. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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