Ultrasound-based hepatic elastography: origins, limitations, and applications.
A reliable, noninvasive marker to help clinicians evaluate hepatic fibrosis is urgently needed. The liver biopsy, an imperfect gold standard, has recognized limitations including sampling error and interobserver variability. Hepatic elastography (HE) is a novel sonographic method for assessing liver...
| Publicado en: | Journal of Clinical Gastroenterology Vol. 44; no. 9; pp. 637 - 646 |
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| Autores principales: | , , , |
| Formato: | research Journal Article |
| Publicado: |
Lippincott Williams & Wilkins
2010 Oct
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104924108&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104924108 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01920790 4BP jtl: Journal of Clinical Gastroenterology issn: 01920790 maglogo: N pubinfo: dt: 2010 Oct vid: 44 iid: 9 pid: 433 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 104924108 104924108 NLM20844365 2010796978 10.1097/MCG.0b013e3181e12c39 NLM20844365 104924108 ppf: 637 ppct: 9 formats: tig: atl: Ultrasound-based hepatic elastography: origins, limitations, and applications. aug: au: Cohen EB Afdhal NH Cohen, Eric B Afdhal, Nezam H affil: Yale University School of Medicine, Department of Digestive Diseases, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA sug: subj: Ultrasonography Methods Liver Cirrhosis Ultrasonography Biopsy Methods Human Liver Cirrhosis Pathology Predictive Value of Tests Prognosis Severity of Illness Indices ab: A reliable, noninvasive marker to help clinicians evaluate hepatic fibrosis is urgently needed. The liver biopsy, an imperfect gold standard, has recognized limitations including sampling error and interobserver variability. Hepatic elastography (HE) is a novel sonographic method for assessing liver stiffness and has excellent accuracy in making the diagnosis of minimal fibrosis and cirrhosis. Several conditions intrinsic to the pathology of the liver compromise the positive predictive value of HE for fibrosis alone including acute hepatitis, obstructive cholestasis, and passive congestion. Technical considerations that hinder the performance of elastography include an advanced body mass index, the presence of ascites and narrow intercostal spaces. Despite these limitations, elastography has a role in staging fibrosis, prognosis of disease outcome, surveillance, and treatment decisions. HE is now being used in lieu of liver biopsy to investigate the natural history of chronic liver diseases. Additional studies are required to better define the appropriate role of HE in clinical practice. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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