Multidetector computed tomography with triple-bolus contrast medium administration protocol for preoperative anatomical and functional assessment of potential living renal donors.
Objective: To evaluate multidetector computed tomography (MDCT) with a triple-bolus contrast administration protocol for preoperative anatomical and functional assessment of living renal donors.Methods: Fifty-five potential living renal donors underwent MDCT of which 27 proceeded to donor nephrectom...
| Publicado en: | European Radiology Vol. 20; no. 11; pp. 2590 - 2600 |
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| Autores principales: | , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Nov2010
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104927344&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104927344 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Nov2010 vid: 20 iid: 11 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104927344 104927344 NLM20582545 2010806999 10.1007/s00330-010-1855-y NLM20582545 104927344 ppf: 2590 ppct: 10 formats: fmt: @attributes: type: P tig: atl: Multidetector computed tomography with triple-bolus contrast medium administration protocol for preoperative anatomical and functional assessment of potential living renal donors. aug: au: Knox MK Rivers-Bowerman MD Bardgett HP Cowan NC Knox, Matthew K Rivers-Bowerman, Michael D Bardgett, Harry P Cowan, Nigel C affil: Faculty of Medicine, UME Office, Health Sciences Centre, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta, Canada T2N 4N1 sug: subj: Contrast Media Administration and Dosage Kidney Radiography Kidney Transplantation Living Donors Tomography, X-Ray Computed Adult Aged Female Human Growth Substances Administration and Dosage Growth Substances Diagnostic Use Kidney Physiology Male Middle Age Radiation Dosage Radionuclide Angiography Radiopharmaceuticals Diagnostic Use Renal Artery Radiography Renal Veins Radiography Sensitivity and Specificity Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Objective: To evaluate multidetector computed tomography (MDCT) with a triple-bolus contrast administration protocol for preoperative anatomical and functional assessment of living renal donors.Methods: Fifty-five potential living renal donors underwent MDCT of which 27 proceeded to donor nephrectomy. A triple-bolus contrast administration protocol was used for simultaneous acquisition of arterial, nephrographic, and excretory phases. MDCT images were independently reviewed in random order by two radiologists blinded to surgical anatomy findings. Diagnostic accuracy for anatomical variants was quantified by sensitivity and specificity. Differential renal function (DRF) was derived from MDCT for 54 patients and compared with technetium-99 m dimercaptosuccinic acid renography (Tc-99 m DMSA).Results: All triple-bolus MDCT examinations were technically adequate. Accessory renal arteries and veins were identified at surgery in 33% (n = 9/27) and 22% (n = 6/27) of donor kidneys. The mean difference between MDCT-derived DRF and DMSA was 0.8% (95% CI 0.1-1.6) with 95% limits of agreement of -4.6% (95% CI -3.3 to -5.9) to 6.3% (95% CI 5.0-7.6). MDCT delivered a mean (SD, range) radiation dose of 9.5 (3.6, 3.6-17.3) mSv.Conclusion: MDCT with a triple-bolus contrast administration provides accurate anatomical and functional evaluation of living renal donors. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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