The culprit lesion and its consequences: combined visualization of the coronary arteries and delayed myocardial enhancement in dual-source CT: a pilot study.
Objective: To assess combined analysis of coronary arteries and delayed myocardial contrast enhancement based on co-registration of coronary CT angiography and late-phase CT and automatic segmentation.Materials and Methods: Co-registration and late enhancement segmentation were applied to coronary C...
| Publicado en: | European Radiology Vol. 20; no. 12; pp. 2834 - 2844 |
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| Autores principales: | , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Dec2010
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104943565&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104943565 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Dec2010 vid: 20 iid: 12 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104943565 55106295 NLM20574631 2010856853 10.1007/s00330-010-1864-x NLM20574631 104943565 ppf: 2834 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: The culprit lesion and its consequences: combined visualization of the coronary arteries and delayed myocardial enhancement in dual-source CT: a pilot study. aug: au: Mahnken AH Bruners P Friman O Hennemuth A Mahnken, Andreas H Bruners, Philipp Friman, Ola Hennemuth, Anja affil: Department of Diagnostic Radiology, University Hospital, RWTH Aachen University, Pauwelsstrasse 30, 52074, Aachen, Germany sug: subj: Algorithms Coronary Angiography Methods Myocardial Infarction Radiography Information Science Methods Radiographic Image Enhancement Methods Subtraction Technique Tomography, X-Ray Computed Methods Aged Animals Female Human Male Pilot Studies Reproducibility of Results Sensitivity and Specificity Swine Aged: 65+ years Female Male ab: Objective: To assess combined analysis of coronary arteries and delayed myocardial contrast enhancement based on co-registration of coronary CT angiography and late-phase CT and automatic segmentation.Materials and Methods: Co-registration and late enhancement segmentation were applied to coronary CT angiography and late-phase CT images from six pigs with acute myocardial infarction (MI) and six patients with chronic MI. MI size was quantified by manual delineation, the established 3SD method, and a new mixture model approach. Correspondence between coronary artery lesions and MI was assessed visually from fused segmentation results.Results: Co-registration was successful in all cases. There was substantial agreement in the number of segments diagnosed with MI, comparing manual delineation and the mixture model for animal (κ = 0.839) and patient studies (κ = 0.770). There were no significant differences between the two methods (P > 0.05). In patients there was a discrepancy between the segmental distribution of MI and empirical coronary artery perfusion in 10/96 segments when compared with the true coronary branching pattern.Conclusion: The mixture model approach is well suited for automated assessment of MI size from late-phase cardiac CT. Fusion imaging eliminates the need for empirical knowledge of the anatomical relationship between the coronary artery lesion and the area of myocardial ischaemia. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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