Whole-body MRI (WB-MRI) versus axial skeleton MRI (AS-MRI) to detect and measure bone metastases in prostate cancer (PCa).
Objective: To compare whole-body MRI (WB-MRI) and axial skeleton MRI (AS-MRI) in detecting and measuring bone metastases in patients with prostate cancer (PCa).Methods: WB-MRI and AS-MRI examinations were performed in 60 patients with PCa at high risk of metastases. Two radiologists separately categ...
| Publicado en: | European Radiology Vol. 20; no. 12; pp. 2973 - 2983 |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Dec2010
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104943579&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104943579 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Dec2010 vid: 20 iid: 12 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104943579 55106299 NLM20661742 2010856867 10.1007/s00330-010-1879-3 NLM20661742 104943579 ppf: 2973 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Whole-body MRI (WB-MRI) versus axial skeleton MRI (AS-MRI) to detect and measure bone metastases in prostate cancer (PCa). aug: au: Lecouvet FE Simon M Tombal B Jamart J Vande Berg BC Simoni P Lecouvet, F E Simon, M Tombal, B Jamart, J Vande Berg, B C Simoni, P affil: Department of Radiology and Medical Imaging, Université Catholique de Louvain, Cliniques Universitaires St Luc, Hippocrate Avenue 10/2942, 1200, Brussels, Belgium sug: subj: Bone Neoplasms Diagnosis Bone Neoplasms Bone and Bones Pathology Magnetic Resonance Imaging Methods Prostatic Neoplasms Diagnosis Diagnostic Imaging Methods Aged Aged, 80 and Over Human Male Middle Age Reproducibility of Results Sensitivity and Specificity Aged: 65+ years Aged, 80 & over Middle Aged: 45-64 years Male ab: Objective: To compare whole-body MRI (WB-MRI) and axial skeleton MRI (AS-MRI) in detecting and measuring bone metastases in patients with prostate cancer (PCa).Methods: WB-MRI and AS-MRI examinations were performed in 60 patients with PCa at high risk of metastases. Two radiologists separately categorised the AS-MRI and WB-MRI as negative or positive for metastases, and measured focal metastases using the "Response evaluation criteria in solid tumours" (RECIST) criteria transposed to bone. One radiologist reviewed all examinations 2 months later. Inter- and intraobserver agreements in establishing the presence/absence of metastases were calculated. Bland-Altman plots were used to assess measurement agreement between AS-MRI and WB-MRI.Results: Strong to perfect inter- and intraobserver agreements were found between AS-MRI and WB-MRI in defining the presence/absence of bone metastases. There were no patients with isolated "peripheral" metastases at WB-MRI, missed at AS-MRI. There was no difference in lesion count between the two radiologists. AS-MRI and WB-MRI provided statistically equivalent RECIST values for one radiologist and slightly lower values at AS-MRI for the other.Conclusions: In our series of PCa patients, AS-MRI and WB-MRI were equivalent in determining the presence/absence of bone metastases and provided similar evaluation of the metastatic burden. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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