Two percent topical phenytoin sodium solution in treating pyoderma gangrenosum: a cohort study.
Oral phenytoin is an extensively used medicine for the treatment of convulsive disorders. Topical phenytoin has also been used for various types of ulcers. To determine the effectiveness of 2% topical phenytoin sodium solution in treating recalcitrant pyoderma gangrenosum. Six patients with treatmen...
| Publicado en: | International Wound Journal Vol. 7; no. 6; pp. 519 - 524 |
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| Autores principales: | , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Dec2010
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104947008&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104947008 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 17424801 1725 jtl: International Wound Journal issn: 17424801 maglogo: Y pubinfo: dt: Dec2010 vid: 7 iid: 6 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 104947008 2010863153 10.1111/j.1742-481X.2010.00725.x NLM20722769 104947008 ppf: 519 ppct: 5 formats: tig: atl: Two percent topical phenytoin sodium solution in treating pyoderma gangrenosum: a cohort study. aug: au: Fonseka, Hewa Ekanayake, Sandeepa Madhujith Bandara Dissanayake, Manel affil: Department of Dermatology, Teaching Hospital, Kandy, Sri Lanka sug: subj: Bandages and Dressings Evaluation Phenytoin Administration and Dosage Pyoderma Gangrenosum Therapy Solutions Administration and Dosage Human Prospective Studies Time Factors Venous Ulcer Wound Care ab: Oral phenytoin is an extensively used medicine for the treatment of convulsive disorders. Topical phenytoin has also been used for various types of ulcers. To determine the effectiveness of 2% topical phenytoin sodium solution in treating recalcitrant pyoderma gangrenosum. Six patients with treatment-resistant pyoderma gangrenosum who attended to Dermatology Unit/Ward were taken to the study and applied topical 2% phenytoin sodium solution to the wounds alone with other systemic therapy. Response to the treatment was assessed weekly. Three patients had idiopathic PG and other three had secondary diseases. At the end of the 4th week four patients showed complete resolution of the ulcers whereas other two patients showed the partial resolution. No adverse effects were noted. Phenytoin sodium 2% solution is beneficial for pyoderma gangrenosum (PG) with various etiologies. It enhanced the healing of the ulcer especially when the patient has treatment resistant disease. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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