A novel approach to prediction of mild obstructive sleep disordered breathing in a population-based sample: the sleep heart health study.

This manuscript considers a data-mining approach for the prediction of mild obstructive sleep disordered breathing, defined as an elevated respiratory disturbance index (RDI), in 5,530 participants in a community-based study, the Sleep Heart Health Study. The prediction algorithm was built using mod...

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Publicado en:Sleep Vol. 33; no. 12; pp. 1641 - 1649
Autores principales: Caffo B, Diener-West M, Punjabi NM, Samet J
Formato: research Journal Article
Publicado: Oxford University Press / USA 2010 Dec 1
Acceso en línea:Ver este registro en EBSCOhost
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        atl: A novel approach to prediction of mild obstructive sleep disordered breathing in a population-based sample: the sleep heart health study.
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          Caffo B
          Diener-West M
          Punjabi NM
          Samet J
      sug:
        subj:
          Sleep Apnea Syndromes Diagnosis
          Sleep Apnea Syndromes Epidemiology
          Age Factors
          Aged
          Boosting Machine Learning Algorithms
          Body Constitution
          Body Mass Index
          Clinical Assessment Tools
          Female
          Human
          Male
          Middle Age
          Predictive Value of Tests
          Prospective Studies
          Risk Factors
          ROC Curve
          Snoring Complications
          Aged: 65+ years
          Middle Aged: 45-64 years
          Female
          Male
      ab: This manuscript considers a data-mining approach for the prediction of mild obstructive sleep disordered breathing, defined as an elevated respiratory disturbance index (RDI), in 5,530 participants in a community-based study, the Sleep Heart Health Study. The prediction algorithm was built using modern ensemble learning algorithms, boosting in specific, which allowed for assessing potential high-dimensional interactions between predictor variables or classifiers. To evaluate the performance of the algorithm, the data were split into training and validation sets for varying thresholds for predicting the probability of a high RDI (>= 7 events per hour in the given results). Based on a moderate classification threshold from the boosting algorithm, the estimated post-test odds of a high RDI were 2.20 times higher than the pre-test odds given a positive test, while the corresponding post-test odds were decreased by 52% given a negative test (sensitivity and specificity of 0.66 and 0.70, respectively). In rank order, the following variables had the largest impact on prediction performance: neck circumference, body mass index, age, snoring frequency, waist circumference, and snoring loudness. CITATION: Caffo B; Diener-West M; Punjabi NM; Samet J. A novel approach to prediction of mild obstructive sleep disordered breathing in a population-based sample: the Sleep Heart Health Study. SLEEP 2010;33(12):1641-1648.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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