Repetitive transorbital alternating current stimulation in optic neuropathy.

Background: Visual field defects after optic nerve damage typically show a limited capacity for spontaneous and treatment-induced recovery. Objective: Repetitive transorbital alternating current stimulation (rtACS) was applied to the damaged optic nerve to evaluate visual functions after stimulation...

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Publicado en:NeuroRehabilitation Vol. 27; no. 4; pp. 335 - 342
Autores principales: Gall C, Fedorov AB, Ernst L, Borrmann A, Sabel BA
Formato: case study pictorial tables/charts Journal Article
Publicado: Sage Publications Inc. 2010
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Sage Publications Inc.
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        atl: Repetitive transorbital alternating current stimulation in optic neuropathy.
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          Gall C
          Fedorov AB
          Ernst L
          Borrmann A
          Sabel BA
        affil: Otto-von-Guericke University of Magdeburg, Medical Faculty, Institute of Medical Psychology, Magdeburg, Germany; Carolin.Gall@med.ovgu.de
      sug:
        subj:
          Optic Nerve Diseases Therapy
          Electric Stimulation Methods
          Treatment Outcomes
          Adult
          Male
          Adult: 19-44 years
          Male
      ab: Background: Visual field defects after optic nerve damage typically show a limited capacity for spontaneous and treatment-induced recovery. Objective: Repetitive transorbital alternating current stimulation (rtACS) was applied to the damaged optic nerve to evaluate visual functions after stimulation. Methods: A 27-years-old male patient suffering left optic nerve atrophy with nearly complete loss of vision 11 years after atypical traumatic damage was treated transorbitally with biphasic 10-15 pulse trains of rtACS (10-30 Hz, < 600 μA, 30-40 min daily for 10 days) which produced phosphenes. Results: After rtACS treatment detection ability of super-threshold stimuli increased from 3.44% to 17.75% and mean perimetric threshold from 0 dB to 2.21 dB at final diagnostics. Conclusion: This improvement of vision may be due to increased neuronal synchronization, possibly involving strengthening of synaptic transmission along the central visual pathway.
      pubtype: Academic Journal
      doctype:
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        pictorial
        tables/charts
        Journal Article
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    language: English
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