The diagnostic accuracy of US, CT, MRI and 1H-MRS for the evaluation of hepatic steatosis compared with liver biopsy: a meta-analysis.
Objective: To meta-analyse the diagnostic accuracy of US, CT, MRI and 1H-MRS for the evaluation of hepatic steatosis.Methods: From a comprehensive literature search in MEDLINE, EMBASE, CINAHL and Cochrane (up to November 2009), articles were selected that investigated the diagnostic performance imag...
| Publicado en: | European Radiology Vol. 21; no. 1; pp. 87 - 98 |
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| Autores principales: | , , , , , , , |
| Formato: | research systematic review Journal Article |
| Publicado: |
Springer Nature
Jan2011
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104983783&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104983783 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Jan2011 vid: 21 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104983783 55530737 NLM20680289 2010906089 10.1007/s00330-010-1905-5 NLM20680289 PMC2995875 104983783 ppf: 87 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: The diagnostic accuracy of US, CT, MRI and 1H-MRS for the evaluation of hepatic steatosis compared with liver biopsy: a meta-analysis. aug: au: Bohte AE van Werven JR Bipat S Stoker J Bohte, Anneloes E van Werven, Jochem R Bipat, Shandra Stoker, Jaap affil: Department of Radiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands sug: subj: Fatty Liver Diagnosis Liver Neoplasms Diagnosis Magnetic Resonance Imaging Tomography, X-Ray Computed Ultrasonography Adolescence Adult Aged Aged, 80 and Over Child CINAHL Database Cochrane Library Embase Female Human Liver Neoplasms Pathology Male Medline Meta Analysis Middle Age Sensitivity and Specificity Systematic Review Adolescent: 13-18 years Adult: 19-44 years Aged: 65+ years Aged, 80 & over Child: 6-12 years Middle Aged: 45-64 years Female Male ab: Objective: To meta-analyse the diagnostic accuracy of US, CT, MRI and 1H-MRS for the evaluation of hepatic steatosis.Methods: From a comprehensive literature search in MEDLINE, EMBASE, CINAHL and Cochrane (up to November 2009), articles were selected that investigated the diagnostic performance imaging techniques for evaluating hepatic steatosis with histopathology as the reference standard. Cut-off values for the presence of steatosis on liver biopsy were subdivided into four groups: (1) >0, >2 and >5% steatosis; (2) >10, >15 and >20%; (3) >25, >30 and >33%; (4) >50, >60 and >66%. Per group, summary estimates for sensitivity and specificity were calculated. The natural-logarithm of the diagnostic odds ratio (lnDOR) was used as a single indicator of test performance.Results: 46 articles were included. Mean sensitivity estimates for subgroups were 73.3-90.5% (US), 46.1-72.0% (CT), 82.0-97.4% (MRI) and 72.7-88.5% (1H-MRS). Mean specificity ranges were 69.6-85.2% (US), 88.1-94.6% (CT), 76.1-95.3% (MRI) and 92.0-95.7% (1H-MRS). Overall performance (lnDOR) of MRI and 1H-MRS was better than that for US and CT for all subgroups, with significant differences in groups 1 and 2.Conclusion: MRI and 1H-MRS can be considered techniques of choice for accurate evaluation of hepatic steatosis. pubtype: Academic Journal doctype: meta analysis research systematic review Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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