Validation of population-based disease simulation models: a review of concepts and methods.

Background: Computer simulation models are used increasingly to support public health research and policy, but questions about their quality persist. The purpose of this article is to review the principles and methods for validation of population-based disease simulation models.Methods: We developed...

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Publicado en:BMC Public Health Vol. 10; no. 1; pp. 710 - 711
Autores principales: Kopec, Jacek A, Finès, Philippe, Manuel, Douglas G, Buckeridge, David L, Flanagan, William M, Oderkirk, Jillian, Abrahamowicz, Michal, Harper, Samuel, Sharif, Behnam, Okhmatovskaia, Anya, Sayre, Eric C, Rahman, M Mushfiqur, Wolfson, Michael C
Formato: review Journal Article
Publicado: BioMed Central 2010
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Validation of population-based disease simulation models: a review of concepts and methods.
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        au:
          Kopec, Jacek A
          Finès, Philippe
          Manuel, Douglas G
          Buckeridge, David L
          Flanagan, William M
          Oderkirk, Jillian
          Abrahamowicz, Michal
          Harper, Samuel
          Sharif, Behnam
          Okhmatovskaia, Anya
          Sayre, Eric C
          Rahman, M Mushfiqur
          Wolfson, Michael C
        affil: School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada. jkopec@arthritisresearch.ca
      sug:
        subj:
          Chronic Disease Epidemiology
          Computer Simulation Standards
          Models, Theoretical
          Validation Studies
          Public Health
          Funding Source
      ab: Background: Computer simulation models are used increasingly to support public health research and policy, but questions about their quality persist. The purpose of this article is to review the principles and methods for validation of population-based disease simulation models.Methods: We developed a comprehensive framework for validating population-based chronic disease simulation models and used this framework in a review of published model validation guidelines. Based on the review, we formulated a set of recommendations for gathering evidence of model credibility.Results: Evidence of model credibility derives from examining: 1) the process of model development, 2) the performance of a model, and 3) the quality of decisions based on the model. Many important issues in model validation are insufficiently addressed by current guidelines. These issues include a detailed evaluation of different data sources, graphical representation of models, computer programming, model calibration, between-model comparisons, sensitivity analysis, and predictive validity. The role of external data in model validation depends on the purpose of the model (e.g., decision analysis versus prediction). More research is needed on the methods of comparing the quality of decisions based on different models.Conclusion: As the role of simulation modeling in population health is increasing and models are becoming more complex, there is a need for further improvements in model validation methodology and common standards for evaluating model credibility.
      pubtype: Academic Journal
      doctype:
        review
        Journal Article
      ougenre: Article
    language: English
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