The influence of gender, hand dominance, and upper extremity length on motor evoked potentials.
Unlabelled: Motor evoked potentials (MEPs) induced through transcranial magnetic stimulation (TMS) are susceptible to several sources of variability including gender, hand dominance, and upper extremity length. Conflicting evidence on the relationship between MEPs and subject characteristics has bee...
| Publicado en: | Journal of Clinical Monitoring & Computing Vol. 24; no. 6; pp. 427 - 437 |
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| Autores principales: | , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Dec2010
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105002127&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105002127 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13871307 OHC jtl: Journal of Clinical Monitoring & Computing issn: 13871307 maglogo: N pubinfo: dt: Dec2010 vid: 24 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 105002127 57361090 NLM21110222 2010926430 10.1007/s10877-010-9267-8 NLM21110222 105002127 ppf: 427 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: The influence of gender, hand dominance, and upper extremity length on motor evoked potentials. aug: au: Livingston SC Goodkin HP Ingersoll CD Livingston, Scott C Goodkin, Howard P Ingersoll, Christopher D affil: Department of Rehabilitation Sciences, College of Health Sciences, University of Kentucky, Wethington 204C, Lexington, KY 40536-0200, USA sug: subj: Arm Anatomy and Histology Evoked Potentials, Motor Physiology Dominance, Cerebral Physiology Hand Physiology Movement Physiology Diagnosis, Neurologic Methods Arm Physiology Female Human Male Models, Biological Sex Factors Young Adult Female Male ab: Unlabelled: Motor evoked potentials (MEPs) induced through transcranial magnetic stimulation (TMS) are susceptible to several sources of variability including gender, hand dominance, and upper extremity length. Conflicting evidence on the relationship between MEPs and subject characteristics has been reported.Objective: The purposes of this study were to determine if MEPs are different between genders and between right- and left-hand dominant subjects, and to determine if MEPs are correlated with upper extremity length.Methods: Using a case-control design, we recorded MEPs from 45 healthy subjects (age 21.6 ± 2.0 years; 24 females, 21 males) with a MagStim200 stimulating coil positioned over the primary motor cortex. Evoked responses were recorded by surface EMG electrodes from the abductor pollicis brevis, abductor digiti minimi and first dorsal interosseous muscles contralateral to the site of TMS. Evoked responses were analyzed to determine motor thresholds, latencies and amplitudes. Central motor conduction time (CMCT) was estimated from MEP, M response, and F wave latencies.Results: Gender and hand dominance did not significantly influence thresholds, MEP amplitudes, or CMCT (P > .05). MEP latencies were moderately correlated with upper extremity length (R = .62 right median, R = .50 left median, R = .45 right ulnar, R = .51 left ulnar MEP latency, P < .01). An ANCOVA using upper extremity length as the covariate demonstrated no significant differences between genders (Wilk's λ = .89, F = 2.45, P = .10). After adjusting MEP latencies to upper limb length, no significant differences were observed between dominant and non-dominant limbs (F = .002, P = .97 median, and F = .03, P = .56 ulnar) nor between genders (F = 2.7, P = .11 median; F = .05, P = .82 ulnar).Conclusions: Variability in MEP latencies between genders was due to differences in upper extremity length. Adjusting MEP latencies to upper limb length is recommended for more accurate comparison and meaningful interpretation between subjects. Hand dominance and gender do not significantly influence motor thresholds, MEP amplitude, or CMCT. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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