A randomized, controlled trial of computer-assisted cognitive remediation for schizophrenia.
Objective: There is considerable interest in cognitive remediation for schizophrenia. Our study aimed to evaluate, in a large sample of patients with schizophrenia, the interest of a computer-assisted cognitive remediation program on cognitive performances of patients as well as in clinical and func...
| Published in: | Schizophrenia Research Vol. 125; no. 2/3; pp. 284 - 291 |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , |
| Format: | research randomized controlled trial Journal Article |
| Published: |
Elsevier B.V.
Feb2011
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105003633&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105003633 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09209964 3PT jtl: Schizophrenia Research issn: 09209964 maglogo: N pubinfo: dt: Feb2011 vid: 125 iid: 2/3 pid: 1004 pub: Elsevier B.V. artinfo: ui: 105003633 NLM21094025 2010928086 10.1016/j.schres.2010.10.023 NLM21094025 105003633 ppf: 284 ppct: 7 formats: tig: atl: A randomized, controlled trial of computer-assisted cognitive remediation for schizophrenia. aug: au: d'Amato T Bation R Cochet A Jalenques I Galland F Giraud-Baro E Pacaud-Troncin M Augier-Astolfi F Llorca PM Saoud M Brunelin J d'Amato, Thierry Bation, Remy Cochet, Alain Jalenques, Isabelle Galland, Fabienne Giraud-Baro, Elisabeth Pacaud-Troncin, Michele Augier-Astolfi, Françoise Llorca, Pierre-Michel affil: Université de Lyon, Lyon, F-69003, France sug: subj: Cognition Disorders Therapy Computer-Assisted Instruction Psychology Schizophrenia Therapy Adult Cognition Disorders Diagnosis Cognition Disorders Psychosocial Factors Double-Blind Studies Female France Human Male Neuropsychological Tests Prospective Studies Randomized Controlled Trials Remedial Teaching Schizophrenia Diagnosis Adult: 19-44 years Female Male ab: Objective: There is considerable interest in cognitive remediation for schizophrenia. Our study aimed to evaluate, in a large sample of patients with schizophrenia, the interest of a computer-assisted cognitive remediation program on cognitive performances of patients as well as in clinical and functional outcome.Method: Seventy-seven patients with remitted schizophrenia were randomly assigned to 14 2-hours individual sessions of computer-assisted cognitive remediation (n=39) or a control condition (n=38). Remediation was performed using RehaCom ® software. Four procedures were chosen to train four cognitive functions involved in different stages of the information processing: attention/concentration, working memory, logic, and executive functions. Primary outcomes were remediation exercise metrics, neuropsychological composites (episodic memory, working memory, attention, executive functioning, and processing speed), clinical and community functioning measures.Results: Cognitive performances concerning Attention/vigilance, verbal working memory and verbal learning memory and reasoning/problem solving improved significantly in the remediation condition when no difference was reported in the control condition between the 2 assessments. However, there were no significant benefits of cognitive remediation on non-verbal working memory and learning and speed of processing or functional outcome measures.Conclusions: Cognitive remediation for people with schizophrenia was effective in improving performance, but the benefits of training did not generalize to functional outcome measures. Long term follow-up studies are needed to confirm the maintenance of such improvements. pubtype: Academic Journal doctype: research randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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