Dynamic Change of Mitral Annular Geometry and Motion in Ischemic Mitral Regurgitation Assessed by a Computerized 3D Echo Method.

Objective: In patients with ischemic mitral regurgitation (IMR), we assessed dynamic changes in mitral annular geometry and motion during the cardiac cycle, and examined their association with the severity of IMR, using our computerized three-dimensional (3D) echo method. Methods: Real-time 3D echo...

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Publicado en:Echocardiography Vol. 27; no. 9; pp. 1069 - 1078
Autores principales: Daimon M, Saracino G, Fukuda S, Koyama Y, Kwan J, Song J, Agler DA, Gillinov AM, Thomas JD, Shiota T
Formato: diagnostic images research tables/charts Journal Article
Publicado: Wiley-Blackwell Oct2010
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2010
      vid: 27
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Dynamic Change of Mitral Annular Geometry and Motion in Ischemic Mitral Regurgitation Assessed by a Computerized 3D Echo Method.
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        au:
          Daimon M
          Saracino G
          Fukuda S
          Koyama Y
          Kwan J
          Song J
          Agler DA
          Gillinov AM
          Thomas JD
          Shiota T
        affil: Cleveland Clinic Foundation, Cleveland, Ohio
      sug:
        subj:
          Mitral Valve Insufficiency Diagnosis
          Echocardiography, Three-Dimensional
          Human
          Descriptive Statistics
          P-Value
          Middle Age
          Male
          Female
          Unpaired T-Tests
          Repeated Measures
          Analysis of Variance
          Regression
          Adult
          Middle Aged: 45-64 years
          Adult: 19-44 years
          Male
          Female
      ab: Objective: In patients with ischemic mitral regurgitation (IMR), we assessed dynamic changes in mitral annular geometry and motion during the cardiac cycle, and examined their association with the severity of IMR, using our computerized three-dimensional (3D) echo method. Methods: Real-time 3D echo was performed in 12 normal controls and 25 patients with IMR. The saddle-shaped annulus was reconstructed in every 3D volume/frame during a cardiac cycle. For each 3D volume/frame, we assessed the mitral annular area (MAA) and the annular contraction that was expressed as the percentage of the largest MAA accounted for by the change in MAA from largest to smallest calculated value. Results: In IMR patients, the minimum MAA occurred in late-systole, while it occurred in early-systole in the controls. IMR patients had a larger minimum MAA (6.7 ± 1.3 vs. 3.6 ± 0.8 cm, P < 0.001) and reduced annular contraction (23.0 ± 6.5 vs. 42.6 ± 7.0%, P < 0.001) when compared to controls. Both minimum MAA and annular contraction had significant correlations with IMR severity (r = 0.67 and r = 0.78, P < 0.001 for both). Conclusion: The contraction of the dilated mitral annulus occurred in late-systole in patients with IMR. The alterations of annular geometry and motion may be associated with the development of IMR. (Echocardiography 2010;27:1069-1077)
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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