Effects of supplementation with different edible oils on cutaneous wound healing.
Fatty acids are bioactive molecules, but their effects on cutaneous wound healing are not well understood. Our aim was to investigate the effects of supplementation with edible oils on cutaneous healing. Thirty days before wounding, rats were started on daily supplements of sunflower oil, linseed oi...
| Publicado en: | Wound Repair & Regeneration Vol. 18; no. 6; pp. 629 - 637 |
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| Autores principales: | , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Nov/Dec2010
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105013112&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105013112 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10671927 DPV jtl: Wound Repair & Regeneration issn: 10671927 maglogo: Y pubinfo: dt: Nov/Dec2010 vid: 18 iid: 6 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 105013112 105013112 2010849113 10.1111/j.1524-475X.2010.00617.x NLM20868383 105013112 ppf: 629 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Effects of supplementation with different edible oils on cutaneous wound healing. aug: au: Otranto M Do Nascimento AP Monte-Alto-Costa A affil: Laboratory of Tissue Repair, Department of Histology and Embryology, State University of Rio de Janeiro, Rio de Janeiro, Brazil sug: subj: Skin Injuries Wounds and Injuries Diet Therapy Dietary Supplements Oils Rats Animal Studies Models, Biological Flowers Linseed Oil Fish Oils Wound Healing Physiology Inflammation Physiopathology Immunohistochemistry Descriptive Statistics One-Way Analysis of Variance Post Hoc Analysis Data Analysis Software Treatment Outcomes Funding Source ab: Fatty acids are bioactive molecules, but their effects on cutaneous wound healing are not well understood. Our aim was to investigate the effects of supplementation with edible oils on cutaneous healing. Thirty days before wounding, rats were started on daily supplements of sunflower oil, linseed oil, fish oil, or water. Supplementation lasted until euthanasia. On day 0, an excisional wound was made on the back of each animal. Fourteen days later, the animals were euthanized, and the wound and adjacent skin were collected. Wound closure was higher in the control group compared with the other groups at days 7 and 14. Inflammatory cells were abundant in the control, linseed, and fish groups, but scarce in the sunflower group. Large numbers of myofibroblasts were observed in the control and sunflower groups. The linseed and fish groups presented a high density of dilated blood vessels. The control and sunflower groups showed a moderate density of collagen fibers; a high density of fibers was observed in the linseed and fish groups. Hydroxyproline levels were lowest in the control and sunflower groups. Supplementation with different types of edible oils delayed wound closure and affected the inflammatory infiltrate and collagen deposition. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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