Incorporation of Preprocedural PET into CT-Guided Radiofrequency Ablation of Hepatic Metastases: a Nonrigid Image Registration Validation Study.
This study evaluates the accuracy of augmenting initial intraprocedural computed tomography (CT) during radiofrequency ablation (RFA) of hepatic metastases with preprocedural positron emission tomography (PET) through a hardware-accelerated implementation of an automatic nonrigid PET-CT registration...
| Published in: | Journal of Digital Imaging Vol. 23; no. 6; pp. 780 - 793 |
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| Main Authors: | , , , |
| Format: | equations & formulas pictorial research tables/charts Journal Article |
| Published: |
Springer Nature
Dec2010
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105017028&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105017028 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 08971889 DOQ jtl: Journal of Digital Imaging issn: 08971889 maglogo: N pubinfo: dt: Dec2010 vid: 23 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 105017028 55128921 10.1007/s10278-009-9204-x NLM19472008 105017028 ppf: 780 ppct: 13 formats: fmt: @attributes: type: P tig: atl: Incorporation of Preprocedural PET into CT-Guided Radiofrequency Ablation of Hepatic Metastases: a Nonrigid Image Registration Validation Study. aug: au: Lei P Dandekar O Widlus D Shekhar R affil: Department of Diagnostic Radiology and Nuclear Medicine, School of Medicine, University of Maryland, 22 S. Greene St. Baltimore 21201 sug: subj: Catheter Ablation Tomography, X-Ray Computed Neoplasm Metastasis Therapy Liver Neoplasms Therapy Liver Radiography Radiographic Image Enhancement Tomography, Emission-Computed Therapy, Computer Assisted Methods Radiography, Interventional Methods Human Algorithms Radiographic Image Interpretation, Computer-Assisted Retrospective Design Interrater Reliability P-Value Evaluation Research ab: This study evaluates the accuracy of augmenting initial intraprocedural computed tomography (CT) during radiofrequency ablation (RFA) of hepatic metastases with preprocedural positron emission tomography (PET) through a hardware-accelerated implementation of an automatic nonrigid PET-CT registration algorithm. The feasibility of augmenting intraprocedural CT with preprocedural PET to improve localization of CT-invisible but PET-positive tumors with images from actual RFA was explored. Preprocedural PET and intraprocedural CT images from 18 cases of hepatic RFA were included. All PET images in the study originated from a hybrid PET/CT scanner, and PET-CT registration was performed in two ways: (1) direct registration of preprocedural PET with intraprocedural CT and (2) indirect registration of preprocedural CT (i.e., the CT of hybrid PET/CT scan) with intraprocedural CT. A hardware-accelerated registration took approximately 2 min. Calculated registration errors were 7.0 and 8.4 mm for the direct and indirect methods, respectively. Overall, the direct registration was found to be statistically not distinct from that performed by a group of clinical experts. The accuracy, execution speed, and compactness of our implementation of nonrigid image registration suggest that existing PET can be overlaid on intraprocedural CT, promising a novel, technically feasible, and clinically viable approach for PET augmentation of CT guidance of RFA. pubtype: Academic Journal doctype: equations & formulas pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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