Differentiation between true focal liver lesions and pseudolesions in patients with fatty liver: evaluation of helical CT criteria.
Objective: To determine the potential of helical CT for differentiating true lesions from pseudolesions in patients with fatty liver.Methods: Helical CT of 44 patients with diffuse fatty liver (22 with true lesions; 22 with pseudolesions) were reviewed by two observers with regard to morphological f...
| Publicado en: | European Radiology Vol. 20; no. 7; pp. 1726 - 1738 |
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| Autores principales: | , , , , , , , , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Jul2010
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105025195&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105025195 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Jul2010 vid: 20 iid: 7 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 105025195 51242151 NLM20084385 2010681296 10.1007/s00330-009-1708-8 NLM20084385 105025195 ppf: 1726 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Differentiation between true focal liver lesions and pseudolesions in patients with fatty liver: evaluation of helical CT criteria. aug: au: Soyer P Sirol M Fargeaudou Y Duchat F Hamzi L Boudiaf M Aout M Guerrache Y Vicaut E Rymer R Soyer, Philippe Sirol, Marc Fargeaudou, Yann Duchat, Florent Hamzi, Lounis Boudiaf, Mourad Aout, Mounir Guerrache, Youcef Vicaut, Eric Rymer, Roland affil: Departments of Abdominal Imaging, Lariboisière Hospital-AP-HP-GHU Nord and University Paris 7, Paris, France sug: subj: Fatty Liver Radiography Liver Neoplasms Radiography Tomography, X-Ray Computed Diagnosis, Differential Female Human Liver Neoplasms Diagnosis Male Middle Age Middle Aged: 45-64 years Female Male ab: Objective: To determine the potential of helical CT for differentiating true lesions from pseudolesions in patients with fatty liver.Methods: Helical CT of 44 patients with diffuse fatty liver (22 with true lesions; 22 with pseudolesions) were reviewed by two observers with regard to morphological features of visible lesions. Univariate analysis was used to detect discriminating criteria for the diagnosis of true lesions.Results: Interobserver agreement was excellent for 9/10 morphological criteria (kappa = 0.831-1). True lesions were more frequently distant from the liver capsule (50.00% vs. 4.55%), located in the right lobe (72.73% vs. 31.82%), round (86.36% vs. 54.55%), heterogeneous (27.27% vs. 0.00%) and had ill-defined margins (40.91% vs. 13.64%) compared with pseudolesions (P < 0.05). Using univariate analysis, a location distant from the liver capsule was the most discriminating variable to differentiate between true and pseudolesions (P = 0.0060). Hyperattenuating content and round shape were the most sensitive criteria (sensitivity = 90.91% and 86.36%, respectively) for the diagnosis of true lesions, and heterogeneity, vascular displacement and encapsulation were the three most specific ones (specificity = 100.00%). Best accuracy was obtained with an association of the three variables (accuracy = 86.36%).Conclusion: Helical CT provides objective and discriminating morphological criteria to differentiate between true lesions and pseudolesions in patients with fatty liver. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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