K-Bayes reconstruction for perfusion MRI II: modeling and technical development [corrected] [published erratum appears in J DIGIT IMAGING 2010 Oct;23(5):519].
Despite the continued spread of magnetic resonance imaging (MRI) methods in scientific studies and clinical diagnosis, MRI applications are mostly restricted to high-resolution modalities such as structural MRI. While perfusion MRI gives complementary information on blood flow in the brain, its redu...
| Publicado en: | Journal of Digital Imaging Vol. 23; no. 4; pp. 374 - 386 |
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| Autores principales: | , |
| Formato: | diagnostic images equations & formulas research tables/charts Journal Article |
| Publicado: |
Springer Nature
Aug2010
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105049529&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105049529 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 08971889 DOQ jtl: Journal of Digital Imaging issn: 08971889 maglogo: N pubinfo: dt: Aug2010 vid: 23 iid: 4 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 105049529 105049529 2010708794 10.1007/s10278-009-9184-x NLM19274427 105049529 ppf: 374 ppct: 12 formats: fmt: @attributes: type: P tig: atl: K-Bayes reconstruction for perfusion MRI II: modeling and technical development [corrected] [published erratum appears in J DIGIT IMAGING 2010 Oct;23(5):519]. aug: au: Kornak J Young K affil: Department of Radiology and Biomedical Imaging, University of California, San Francisco, 185 Berry Street, Suite 350, San Francisco, CA, 94107, USA. sug: subj: Magnetic Resonance Imaging Methods Radiographic Image Enhancement Radiographic Image Interpretation, Computer-Assisted Evaluation Research Funding Source Human Models, Statistical ab: Despite the continued spread of magnetic resonance imaging (MRI) methods in scientific studies and clinical diagnosis, MRI applications are mostly restricted to high-resolution modalities such as structural MRI. While perfusion MRI gives complementary information on blood flow in the brain, its reduced resolution limits its power for detecting specific disease effects on perfusion patterns. This reduced resolution is compounded by artifacts such as partial volume effects, Gibbs ringing, and aliasing, which are caused by necessarily limited k-space sampling and the subsequent use of discrete Fourier transform (DFT) reconstruction. Here, a Bayesian modeling procedure (K-Bayes) is developed for the reconstruction of perfusion MRI. The K-Bayes approach combines a process model for the MRI signal in k-space with a Markov random field prior distribution that incorporates high-resolution segmented structural MRI information. A simulation study, described in Part I (Concepts and Applications), was performed to determine qualitative and quantitative improvements in K-Bayes reconstructed images compared with those obtained via DFT. The improvements were validated using in vivo perfusion MRI data of the human brain. The K-Bayes reconstructed images were demonstrated to provide reduced bias, increased precision, greater effect sizes, and higher resolution than those obtained using DFT. pubtype: Academic Journal doctype: diagnostic images equations & formulas research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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