Improved pediatric MR imaging with compressed sensing.

Purpose: To develop a method that combines parallel imaging and compressed sensing to enable faster and/or higher spatial resolution magnetic resonance (MR) imaging and show its feasibility in a pediatric clinical setting.Materials and Methods: Institutional review board approval was obtained for th...

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Publicado en:Radiology Vol. 256; no. 2; pp. 607 - 617
Autores principales: Vasanawala SS, Alley MT, Hargreaves BA, Barth RA, Pauly JM, Lustig M, Vasanawala, Shreyas S, Alley, Marcus T, Hargreaves, Brian A, Barth, Richard A, Pauly, John M, Lustig, Michael
Formato: research Journal Article
Publicado: Radiological Society of North America 2010 Aug
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2010 Aug
      vid: 256
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      pub: Radiological Society of North America
      place: Oak Brook, Illinois
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        atl: Improved pediatric MR imaging with compressed sensing.
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          Vasanawala SS
          Alley MT
          Hargreaves BA
          Barth RA
          Pauly JM
          Lustig M
          Vasanawala, Shreyas S
          Alley, Marcus T
          Hargreaves, Brian A
          Barth, Richard A
          Pauly, John M
          Lustig, Michael
        affil: Department of Pediatric Radiology, Stanford University School of Medicine, 725 Welch Rd, Room 1679, Stanford, CA 94305-5913, USA
      sug:
        subj:
          Algorithms
          Image Processing, Computer Assisted Methods
          Image Enhancement Methods
          Image Interpretation, Computer Assisted Methods
          Magnetic Resonance Imaging Methods
          Adolescence
          Child
          Child, Preschool
          Female
          Human
          Infant
          Infant, Newborn
          Male
          Reproducibility of Results
          Sensitivity and Specificity
          Adolescent: 13-18 years
          Child: 6-12 years
          Child, Preschool: 2-5 years
          Infant: 1-23 months
          Infant, Newborn: birth-1 month
          Female
          Male
      ab: Purpose: To develop a method that combines parallel imaging and compressed sensing to enable faster and/or higher spatial resolution magnetic resonance (MR) imaging and show its feasibility in a pediatric clinical setting.Materials and Methods: Institutional review board approval was obtained for this HIPAA-compliant study, and informed consent or assent was given by subjects. A pseudorandom k-space undersampling pattern was incorporated into a three-dimensional (3D) gradient-echo sequence; aliasing then has an incoherent noiselike pattern rather than the usual coherent fold-over wrapping pattern. This k-space-sampling pattern was combined with a compressed sensing nonlinear reconstruction method that exploits the assumption of sparsity of medical images to permit reconstruction from undersampled k-space data and remove the noiselike aliasing. Thirty-four patients (15 female and 19 male patients; mean age, 8.1 years; range, 0-17 years) referred for cardiovascular, abdominal, and knee MR imaging were scanned with this 3D gradient-echo sequence at high acceleration factors. Obtained k-space data were reconstructed with both a traditional parallel imaging algorithm and the nonlinear method. Both sets of images were rated for image quality, radiologist preference, and delineation of specific structures by two radiologists. Wilcoxon and symmetry tests were performed to test the hypothesis that there was no significant difference in ratings for image quality, preference, and delineation of specific structures.Results: Compressed sensing images were preferred more often, had significantly higher image quality ratings, and greater delineation of anatomic structures (P < .001) than did images obtained with the traditional parallel reconstruction method.Conclusion: A combination of parallel imaging and compressed sensing is feasible in a clinical setting and may provide higher resolution and/or faster imaging, addressing the challenge of delineating anatomic structures in pediatric MR imaging.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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