Adenomatous colorectal polyps in patients referred for colonoscopy in a regional hospital in Kuwait.

Background/Aim: Adenomatous colorectal polyps (ACPs) are known to be the precursor lesions for colorectal cancer. The aim of the study was to determine the prevalence, endoscopic and pathological features of ACPs in patients referred for colonoscopy. Patients and Methods: The endoscopic and histolog...

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Publicado en:Saudi Journal of Gastroenterology Vol. 16; no. 3; pp. 188 - 194
Autores principales: Al-Enezi SA, Alsurayei SA, Ismail AE, Aly NYA, Ismail WA, Abou-Bakr AA
Formato: research tables/charts Journal Article
Publicado: Wolters Kluwer India Pvt Ltd Jul2010
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: Saudi Journal of Gastroenterology
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      dt: Jul2010
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      pub: Wolters Kluwer India Pvt Ltd
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        2010731367
        10.4103/1319-3767.65194
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        105068184
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        atl: Adenomatous colorectal polyps in patients referred for colonoscopy in a regional hospital in Kuwait.
      aug:
        au:
          Al-Enezi SA
          Alsurayei SA
          Ismail AE
          Aly NYA
          Ismail WA
          Abou-Bakr AA
        affil: Department of Medicine, Ministry of Health, Kuwait
      sug:
        subj:
          Colon
          Colorectal Neoplasms Prevention and Control
          Polyps
          Polyps Pathology
          Rectum
          Adult
          Analysis of Variance
          Chi Square Test
          Colonoscopy
          Confidence Intervals
          Data Analysis Software
          Equipment and Supplies
          Female
          Fisher's Exact Test
          Human
          Kuwait
          Logistic Regression
          Male
          Middle Age
          Polyps Classification
          Retrospective Design
          T-Tests
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Background/Aim: Adenomatous colorectal polyps (ACPs) are known to be the precursor lesions for colorectal cancer. The aim of the study was to determine the prevalence, endoscopic and pathological features of ACPs in patients referred for colonoscopy. Patients and Methods: The endoscopic and histological reports of adult patients who underwent complete colonoscopy in the gastroenterology unit of a regional Kuwaiti hospital between January 2008 and December 2008 were retrospectively studied. The specimens of polyps were reviewed by an experienced pathologist who was blinded to the clinical or endoscopic information. Non-neoplastic polyps were not included in the analysis. Results: Of 530 eligible patients (mean age, 45 years; male-female ratio, 2:1), 54 (10%) had 103 ACPs. Of the patients with ACPs (mean age, 57 years), 43 (80%) were males and 36 (67%) were Kuwaitis. Histopathological examination of the most significant polyp in each patient revealed that 40 (74%) polyps were tubular adenomas (TAs); 11 (20%), tubulovillous (TV) adenomas; and 3 (6%), villous adenomas. High-grade dysplasia was noticed in 4 (10%) adenomas. Fifteen (2.8%) of the 530 patients had advanced ACPs. Logistic regression analysis of some variables and their association with ACPs found that age (P<0.001; OR, 1.9; CI, 1.5-2.3), history of adenoma (P=0.001; OR, 6.4; CI, .2.1-19.4) and being Kuwaitis (P=0.029; OR, 2.1; CI, 1.1-4.1) to be independently associated with ACPs. Conclusion: The most common histological type of ACPs was tubular adenoma. Advancing age, being Kuwaiti nationals and prior removal of ACPs were significantly associated with the occurrence of ACPs.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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