Effects of Mediterranean diets with low and high proportions of phytate-rich foods on the urinary phytate excretion.

BACKGROUND: Important health benefits have been reported recently to phytate intake. This includes the prevention of pathological calcifications such as renal calculi, dental calculi and cardiovascular calcification, due its action as crystallization inhibitor of calcium salts, and as preventive of...

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Publicado en:European Journal of Nutrition Vol. 49; no. 6; pp. 321 - 327
Autores principales: Prieto RM, Fiol M, Perello J, Estruch R, Ros E, Sanchis P, Grases F
Formato: research tables/charts Journal Article
Publicado: Springer Nature Sep2010
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2010
      vid: 49
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      pub: Springer Nature
      place: New York, New York
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        atl: Effects of Mediterranean diets with low and high proportions of phytate-rich foods on the urinary phytate excretion.
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          Prieto RM
          Fiol M
          Perello J
          Estruch R
          Ros E
          Sanchis P
          Grases F
        affil: Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research (IUNICS), University of Balearic Islands, 07122, Palma, Spain, rafelm.prieto@uib.es.
      sug:
        subj:
          Mediterranean Diet
          Phytic Acid Analysis
          Phytic Acid Metabolism
          Urinalysis
          Aged
          Aged, 80 and Over
          Cross Sectional Studies
          Female
          Funding Source
          Human
          Male
          Middle Age
          Questionnaires
          Spain
          T-Tests
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
          Female
          Male
      ab: BACKGROUND: Important health benefits have been reported recently to phytate intake. This includes the prevention of pathological calcifications such as renal calculi, dental calculi and cardiovascular calcification, due its action as crystallization inhibitor of calcium salts, and as preventive of cancer. AIM OF STUDY: The aim of this study was to establish a relation between the intake of phytate, through consumption of typical components of the Mediterranean diet (including nuts), and its excretion in urine. METHODS: This study recruited participants from subjects included in a larger trial (PREDIMED) of food habits, that were assigned to one of two diet groups: (1) the Mediterranean diet with low proportion of phytate-rich food group, where participants were asked to maintain their usual diet; and (2) the Mediterranean diet with high proportion of phytate-rich food group, where participants were asked to increase phytate-rich foods in their diet. Phytate intake was assessed on the basis of a food frequency questionnaire. Urinary phytate excretion was determined in 2-h urine samples. RESULTS: The overall phytate consumption of the Mediterranean diet with high proportion of phytate-rich food group (672 +/- 50 mg) was significantly higher than the Mediterranean diet with low proportion of phytate-rich food group (422 +/- 34 mg), representing a 59% difference. Urinary phytate excretion was also significantly higher (54%) in the Mediterranean diet with high proportion of phytate-rich food group (1,016 +/- 70 mug/L) than the Mediterranean diet with low proportion of phytate-rich food group (659 +/- 45 mug/L). CONCLUSIONS: Mediterranean diets high in whole cereals, legumes and nuts compared to Mediterranean diets low in these phytate-rich foods increase the urinary phytate excretion in humans.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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