Size of AT(n) insertions in promoter region modulates Gmhsp17.6-L mRNA transcript levels.

During earlier experiments, an SSR molecular marker (176 Soy HSP) showing high correlation (70%) with resistance/susceptibility to javanese root-knot nematode Meloidogyne javanica was identified in soybean. After being sequenced, results indicated that the SSR 176 Soy HSP marker was inserted in the...

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Publicado en:Journal of Biomedicine & Biotechnology pp. 847673 - 847674
Autores principales: Fuganti R, Machado Mde F, Lopes VS, Silva JF, Arias CA, Marin SR, Binneck E, Abdelnoor RV, Marcelino FC, Nepomuceno AL
Formato: Journal Article
Publicado: Wiley-Blackwell 2010
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Wiley-Blackwell
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        atl: Size of AT(n) insertions in promoter region modulates Gmhsp17.6-L mRNA transcript levels.
      aug:
        au:
          Fuganti R
          Machado Mde F
          Lopes VS
          Silva JF
          Arias CA
          Marin SR
          Binneck E
          Abdelnoor RV
          Marcelino FC
          Nepomuceno AL
        affil: Genetics and Plant Breeding, Maringá State University (UEM), Colombo Avenue 5790, Paraná Maringá 87020-900, Brazil.
      sug:
        subj:
          DNA
          Proteins
          Plant Diseases
          Genes
          RNA
          Soybeans
      ab: During earlier experiments, an SSR molecular marker (176 Soy HSP) showing high correlation (70%) with resistance/susceptibility to javanese root-knot nematode Meloidogyne javanica was identified in soybean. After being sequenced, results indicated that the SSR 176 Soy HSP marker was inserted in the promoter region of Gmhsp17.6-L gene. It was also detected in this region that resistant genotypes presented insertions between AT(31) and AT(33) in size and susceptible genotypes, AT(9). Gmhsp17.6-L gene coding region presented a perfect match in amino acid sequence in all soybean genotypes. A ribonuclease protection assay showed that Gmhsp17.6-L gene mRNA transcripts were present in all genotypes. A real-time relative quantification (qPCR) indicated in the resistant individuals higher mRNA transcripts levels, which presented in the sequencing more AT(n) insertions. These results suggest that the number of AT(n) insertions inside this promoter region could modulate up or down gene levels. Those findings can lead to the possibility of manipulating, between some limits, the mRNA transcripts levels using different sizes of AT(n) insertions.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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