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DNA-based applications in nanobiotechnology.

Biological molecules such as deoxyribonucleic acid (DNA) have shown great potential in fabrication and construction of nanostructures and devices. The very properties that make DNA so effective as genetic material also make it a very suitable molecule for programmed self-assembly. The use of DNA to...

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Published in:Journal of Biomedicine & Biotechnology pp. 15p - 16
Main Authors: Abu-Salah KM, Ansari AA, Alrokayan SA
Format: pictorial review tables/charts Journal Article
Published: Wiley-Blackwell 2010
Online Access:View this record in EBSCOhost
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      dt: 2010
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2010/715295
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        atl: DNA-based applications in nanobiotechnology.
      aug:
        au:
          Abu-Salah KM
          Ansari AA
          Alrokayan SA
        affil: King Abdullah Institute for Nanotechnology and Centre of Excellence in Biotechnology, King Saud University, PO Box 2454, Riyadh 11451, Saudi Arabia. abusalah@ksu.edu.sa
      sug:
        subj:
          Biology
          DNA
          Nanotechnology
          Nanotechnology Methods
      ab: Biological molecules such as deoxyribonucleic acid (DNA) have shown great potential in fabrication and construction of nanostructures and devices. The very properties that make DNA so effective as genetic material also make it a very suitable molecule for programmed self-assembly. The use of DNA to assemble metals or semiconducting particles has been extended to construct metallic nanowires and functionalized nanotubes. This paper highlights some important aspects of conjugating the unique physical properties of dots or wires with the remarkable recognition capabilities of DNA which could lead to miniaturizing biological electronics and optical devices, including biosensors and probes. Attempts to use DNA-based nanocarriers for gene delivery are discussed. In addition, the ecological advantages and risks of nanotechnology including DNA-based nanobiotechnology are evaluated.
      pubtype: Academic Journal
      doctype:
        pictorial
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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