Changing prevalence of Helicobacter pylori in south of Iran.

Background: The prevalence of Helicobacter pylori has declined rapidly in Asia. This has been shown in both seroprevalence-based and endoscopy-based studies. The present study was conducted to determine the prevalence of gastric infection caused by H. pylori in an Iranian population residing in sout...

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Publicado en:Iranian Journal of Clinical Infectious Diseases Vol. 5; no. 2; pp. 65 - 70
Autores principales: Farshad S, Japoni A, Alborzi A, Zarenezhad M, Ranjbar R
Formato: research tables/charts Journal Article
Publicado: Iranian Journal of Clinical Infectious Diseases Spring2010
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Spring2010
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      pub: Iranian Journal of Clinical Infectious Diseases
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        atl: Changing prevalence of Helicobacter pylori in south of Iran.
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          Farshad S
          Japoni A
          Alborzi A
          Zarenezhad M
          Ranjbar R
        affil: Professor, Alborzi Clinical Microbiology Research Centre, Shiraz University of Medical Sciences, Shiraz, Iran; farshads@sums.ac.ir
      sug:
        subj:
          Helicobacter Infections Epidemiology
          Adolescence
          Adult
          Aged
          Aged, 80 and Over
          Chi Square Test
          Data Analysis Software
          Female
          Funding Source
          Geographic Locations
          Human
          Iran
          Male
          Middle Age
          Prevalence
          Stomach Diseases
          Young Adult
          Adolescent: 13-18 years
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
          Female
          Male
      ab: Background: The prevalence of Helicobacter pylori has declined rapidly in Asia. This has been shown in both seroprevalence-based and endoscopy-based studies. The present study was conducted to determine the prevalence of gastric infection caused by H. pylori in an Iranian population residing in south of Iran. Patients and methods: A total of 522 patients (266 females and 256 males with the mean age of 44.3±13.0, range 18-83 years) underwent endoscopy in Shiraz, southern Iran. The diagnosis of H. pylori infection was established by rapid urease test, culture and gram staining and the gastric disease was confirmed by an expert pathologist. Results: From ulcerative (n=296) and non-ulcerative (n=226) patients, 156 (52.7%) and 94 (41.6%) H. pylori strains were isolated by culture, respectively. The prevalence of H. pylori infection was significantly higher in patients aged 21-30 and >50 years (66.66% and 62.12%, respectively). However, H. pylori was not detected in 22 patients aged less than 20 years. Conclusion: The present study revealed a significant decline in the prevalence of H. pylori infection in the studied population. It seems that in parallel with better therapeutic approaches and elimination of bacteria, an improvement in the personal hygiene and living conditions of the Iranian population contribute to lower prevalence of H. pylori.
      pubtype: Academic Journal
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        tables/charts
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      ougenre: Article
    language: English
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