Consequences of low neonatal iron status due to maternal diabetes mellitus on explicit memory performance in childhood.
Diabetic pregnancies are characterized by chronic metabolic insults, including iron deficiency, that place the developing brain at risk for memory impairment later in life. A behavioral recall paradigm coupled with electrophysiological measures was used to assess the longevity of these effects in 40...
| Publicado en: | Developmental Neuropsychology Vol. 34; no. 6; pp. 762 - 780 |
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| Autores principales: | , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Taylor & Francis Ltd
Nov/Dec2009
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105127471&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105127471 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 87565641 7LP jtl: Developmental Neuropsychology issn: 87565641 maglogo: N pubinfo: dt: Nov/Dec2009 vid: 34 iid: 6 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 105127471 NLM20183732 2010574533 10.1080/87565640903265145 NLM20183732 PMC2829708 105127471 ppf: 762 ppct: 18 formats: tig: atl: Consequences of low neonatal iron status due to maternal diabetes mellitus on explicit memory performance in childhood. aug: au: Riggins T Miller NC Bauer PJ Georgieff MK Nelson CA Riggins, Tracy Miller, Neely C Bauer, Patricia J Georgieff, Michael K Nelson, Charles A affil: Department of Psychology, University of Maryland, College Park, Maryland 20742, USA sug: subj: Anemia, Iron Deficiency Epidemiology Diabetes Mellitus Epidemiology Memory Disorders Epidemiology Mothers Statistics and Numerical Data Child Child, Preschool Female Human Infant, Newborn Male Memory Disorders Diagnosis Neuropsychological Tests Child: 6-12 years Child, Preschool: 2-5 years Infant, Newborn: birth-1 month Female Male ab: Diabetic pregnancies are characterized by chronic metabolic insults, including iron deficiency, that place the developing brain at risk for memory impairment later in life. A behavioral recall paradigm coupled with electrophysiological measures was used to assess the longevity of these effects in 40 3(1/2)-year-old children. When memory demands were high, recall was significantly impaired in the at-risk group and correlated with perinatal measures of iron. Electrophysiological results suggested both encoding and retrieval processes were compromised. These findings support the hypothesis that prenatal iron deficiency leads to alterations in neural development that have a lasting impact on memory ability. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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