Computer-aided detection (CAD) of lung nodules in CT scans: radiologist performance and reading time with incremental CAD assistance.

Objective: The diagnostic performance of radiologists using incremental CAD assistance for lung nodule detection on CT and their temporal variation in performance during CAD evaluation was assessed.Methods: CAD was applied to 20 chest multidetector-row computed tomography (MDCT) scans containing 190...

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Publicado en:European Radiology Vol. 20; no. 3; pp. 549 - 558
Autores principales: Roos JE, Paik D, Olsen D, Liu EG, Chow LC, Leung AN, Mindelzun R, Choudhury KR, Naidich DP, Napel S, Rubin GD, Roos, Justus E, Paik, David, Olsen, David, Liu, Emily G, Chow, Lawrence C, Leung, Ann N, Mindelzun, Robert, Choudhury, Kingshuk R, Naidich, David P
Formato: research Journal Article
Publicado: Springer Nature Mar2010
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Computer-aided detection (CAD) of lung nodules in CT scans: radiologist performance and reading time with incremental CAD assistance.
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          Roos JE
          Paik D
          Olsen D
          Liu EG
          Chow LC
          Leung AN
          Mindelzun R
          Choudhury KR
          Naidich DP
          Napel S
          Rubin GD
          Roos, Justus E
          Paik, David
          Olsen, David
          Liu, Emily G
          Chow, Lawrence C
          Leung, Ann N
          Mindelzun, Robert
          Choudhury, Kingshuk R
          Naidich, David P
        affil: Department of Radiology, Stanford University Medical Center, 300 Pasteur Drive, Room S-072, Stanford, CA 94305-5105, USA
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          Lung Neoplasms Radiography
          Physicians Statistics and Numerical Data
          Professional Competence Statistics and Numerical Data
          Radiographic Image Enhancement Methods
          Tomography, X-Ray Computed Methods
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          Middle Age
          Observer Bias
          Reproducibility of Results
          Sensitivity and Specificity
          Task Performance and Analysis
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          Adolescent: 13-18 years
          Adult: 19-44 years
          Aged: 65+ years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Objective: The diagnostic performance of radiologists using incremental CAD assistance for lung nodule detection on CT and their temporal variation in performance during CAD evaluation was assessed.Methods: CAD was applied to 20 chest multidetector-row computed tomography (MDCT) scans containing 190 non-calcified > or =3-mm nodules. After free search, three radiologists independently evaluated a maximum of up to 50 CAD detections/patient. Multiple free-response ROC curves were generated for free search and successive CAD evaluation, by incrementally adding CAD detections one at a time to the radiologists' performance.Results: The sensitivity for free search was 53% (range, 44%-59%) at 1.15 false positives (FP)/patient and increased with CAD to 69% (range, 59-82%) at 1.45 FP/patient. CAD evaluation initially resulted in a sharp rise in sensitivity of 14% with a minimal increase in FP over a time period of 100 s, followed by flattening of the sensitivity increase to only 2%. This transition resulted from a greater prevalence of true positive (TP) versus FP detections at early CAD evaluation and not by a temporal change in readers' performance. The time spent for TP (9.5 s +/- 4.5 s) and false negative (FN) (8.4 s +/- 6.7 s) detections was similar; FP decisions took two- to three-times longer (14.4 s +/- 8.7 s) than true negative (TN) decisions (4.7 s +/- 1.3 s).Conclusions: When CAD output is ordered by CAD score, an initial period of rapid performance improvement slows significantly over time because of non-uniformity in the distribution of TP CAD output and not to a changing reader performance over time.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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