A comparison amongst three rapid urease tests to diagnose Helicobacter pylori infection in 375 consecutive dyspeptic.
Rapid diagnostic tools for Helicobacter pylori are important in endoscopy. To assess the accuracy of a new 5-min rapid urease test (UFT300, ABS Cernusco, sul Naviglio, Italy) compared with the 1-h Pyloritek (Serim Laboratories, Elkhart, IN) and the 24-h CLO test (Kimberly-Clark Ballard Medical Produ...
| Publicado en: | Internal & Emergency Medicine Vol. 5; no. 1; pp. 41 - 48 |
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| Autores principales: | , , , , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Feb2010
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105128469&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105128469 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18280447 46A5 jtl: Internal & Emergency Medicine issn: 18280447 maglogo: N pubinfo: dt: Feb2010 vid: 5 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 105128469 NLM20082190 2010575662 10.1007/s11739-009-0344-2 NLM20082190 105128469 ppf: 41 ppct: 7 formats: tig: atl: A comparison amongst three rapid urease tests to diagnose Helicobacter pylori infection in 375 consecutive dyspeptic. aug: au: Vaira D Gatta L Ricci C Perna F Saracino I Fiorini G Castelli V Holton J Vaira, Dino Gatta, Luigi Ricci, Chiara Perna, Federico Saracino, Ilaria Fiorini, Giulia Castelli, Valentina Holton, John affil: Department of Internal Medicine and Gastroenterology, S. Orsola Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy sug: subj: Dyspepsia Microbiology Helicobacter Infections Diagnosis Reagent Kits, Diagnostic Urease Analysis Adult Aged Breath Tests False Negative Results Female Gastroscopy Helicobacter Infections Pathology Human Male Middle Age Prospective Studies Sensitivity and Specificity Urea Analysis Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Rapid diagnostic tools for Helicobacter pylori are important in endoscopy. To assess the accuracy of a new 5-min rapid urease test (UFT300, ABS Cernusco, sul Naviglio, Italy) compared with the 1-h Pyloritek (Serim Laboratories, Elkhart, IN) and the 24-h CLO test (Kimberly-Clark Ballard Medical Products, Roswell, GA), consecutive dyspeptic patients referred to our unit for endoscopy were prospectively studied. All patients underwent a 13C-urea-breath test, histology and the UFT300 (ABS; Cernusco, sul Naviglio, Italy). Two additional rapid urease tests were performed. Patients were deemed infected when both 13C-UBT and histology were positive. Rapid urease tests were read at 1, 5, and 60 min, respectively. Of the 375 enrolled patients, 45.3% were infected with H. pylori. The sensitivity of the new 5-min rapid urease test 300 was 90.3, 94.5, and 96.2% at 1, 5, and 60 min, respectively (specificity 100%). The Pyloritek and the new 5-min rapid urease test were comparable, but the CLO test was not reliable at 5 and 60 min. In conclusion, the new 5-min rapid urease test is comparable to the Pyloritek test, but the CLO test is significantly less sensitive at early time points. Reading the test results at 1 min may increase false-negative results with decreasing sensitivity. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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