Computer-assisted detection of pulmonary embolism: evaluation of pulmonary CT angiograms performed in an on-call setting.

Purpose: The purpose of the study was to assess the stand-alone performance of computer-assisted detection (CAD) for evaluation of pulmonary CT angiograms (CTPA) performed in an on-call setting.Methods: In this institutional review board-approved study, we retrospectively included 292 consecutive CT...

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Published in:European Radiology Vol. 20; no. 4; pp. 801 - 807
Main Authors: Wittenberg R, Peters JF, Sonnemans JJ, Prokop M, Schaefer-Prokop CM, Wittenberg, Rianne, Peters, Joost F, Sonnemans, Jeroen J, Prokop, Mathias, Schaefer-Prokop, Cornelia M
Format: research Journal Article
Published: Springer Nature Apr2010
Online Access:View this record in EBSCOhost
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      dt: Apr2010
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      pub: Springer Nature
      place: New York, New York
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        atl: Computer-assisted detection of pulmonary embolism: evaluation of pulmonary CT angiograms performed in an on-call setting.
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          Wittenberg R
          Peters JF
          Sonnemans JJ
          Prokop M
          Schaefer-Prokop CM
          Wittenberg, Rianne
          Peters, Joost F
          Sonnemans, Jeroen J
          Prokop, Mathias
          Schaefer-Prokop, Cornelia M
        affil: Department of Radiology, Academic Medical Centre, Amsterdam, The Netherlands
      sug:
        subj:
          Health Care Delivery Statistics and Numerical Data
          Angiography Statistics and Numerical Data
          Information Science Methods
          Pulmonary Embolism Epidemiology
          Pulmonary Embolism Radiography
          Radiographic Image Interpretation, Computer-Assisted Methods
          Tomography, X-Ray Computed Statistics and Numerical Data
          Adolescence
          Adult
          Aged
          Aged, 80 and Over
          Algorithms
          Artificial Intelligence
          Female
          Human
          Male
          Middle Age
          Netherlands
          Radiographic Image Enhancement Methods
          Reproducibility of Results
          Sensitivity and Specificity
          Young Adult
          Adolescent: 13-18 years
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
          Female
          Male
      ab: Purpose: The purpose of the study was to assess the stand-alone performance of computer-assisted detection (CAD) for evaluation of pulmonary CT angiograms (CTPA) performed in an on-call setting.Methods: In this institutional review board-approved study, we retrospectively included 292 consecutive CTPA performed during night shifts and weekends over a period of 16 months. Original reports were compared with a dedicated CAD system for pulmonary emboli (PE). A reference standard for the presence of PE was established using independent evaluation by two readers and consultation of a third experienced radiologist in discordant cases.Results: Original reports had described 225 negative studies and 67 positive studies for PE. CAD found PE in seven patients originally reported as negative but identified by independent evaluation: emboli were located in segmental (n = 2) and subsegmental arteries (n = 5). The negative predictive value (NPV) of the CAD algorithm was 92% (44/48). On average there were 4.7 false positives (FP) per examination (median 2, range 0-42). In 72% of studies <or=5 FP were found, 13% of studies had >or=10 FP.Conclusion: CAD identified small emboli originally missed under clinical conditions and found 93% of the isolated subsegmental emboli. On average there were 4.7 FP per examination.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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