Efficacy of Lactic Acid Bacteria (LAB) supplement in management of constipation among nursing home residents.

Background: Constipation is a significant problem in the elderly, specifically nursing home and/or extended-care facility residents are reported to suffer from constipation. Lactic acid bacteria (LAB) are beneficial probiotic organisms that contribute to improved nutrition, microbial balance, and im...

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Publicado en:Nutrition Journal Vol. 9; pp. 5 - 6
Autores principales: An HM, Baek EH, Jang S, Lee do K, Kim MJ, Kim JR, Lee KO, Park JG, Ha NJ, An, Hyang Mi, Baek, Eun Hye, Jang, Seok, Lee, Do Kyung, Kim, Mi Jin, Kim, Jung Rae, Lee, Kang Oh, Park, Jong Gi, Ha, Nam Joo
Formato: research Journal Article
Publicado: BioMed Central 2010
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Efficacy of Lactic Acid Bacteria (LAB) supplement in management of constipation among nursing home residents.
      aug:
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          An HM
          Baek EH
          Jang S
          Lee do K
          Kim MJ
          Kim JR
          Lee KO
          Park JG
          Ha NJ
          An, Hyang Mi
          Baek, Eun Hye
          Jang, Seok
          Lee, Do Kyung
          Kim, Mi Jin
          Kim, Jung Rae
          Lee, Kang Oh
          Park, Jong Gi
          Ha, Nam Joo
        affil: Department of Pharmacy, Sahmyook University, Seoul 139-742, Republic of Korea
      sug:
        subj:
          Bifidobacterium
          Constipation Drug Therapy
          Dietary Supplements
          Lactobacillus Acidophilus
          Nursing Homes
          Gram-Positive Bacteria
          Adult
          Age Factors
          Aged
          Chronic Disease
          Constipation Microbiology
          Feces Microbiology
          Female
          Glycoside Hydrolases Drug Effects
          Glycoside Hydrolases Metabolism
          Human
          Intestines Drug Effects
          Intestines Microbiology
          South Korea
          Male
          Questionnaires
          Treatment Outcomes
          Enzymes Drug Effects
          Enzymes Metabolism
          Urease Drug Effects
          Urease Metabolism
          Young Adult
          Adult: 19-44 years
          Aged: 65+ years
          Female
          Male
      ab: Background: Constipation is a significant problem in the elderly, specifically nursing home and/or extended-care facility residents are reported to suffer from constipation. Lactic acid bacteria (LAB) are beneficial probiotic organisms that contribute to improved nutrition, microbial balance, and immuno-enhancement of the intestinal tract, as well as diarrhea and constipation effect. The objective of this study was to investigate the efficacy of this LAB supplement in the management of nursing home residents.Methods: Nineteen subjects (8M, 11F; mean age 77.1 +/- 10.1) suffering with chronic constipation were assigned to receive LAB (3.0 x 10(11) CFU/g) twice (to be taken 30 minutes after breakfast and dinner) a day for 2 weeks in November 2008. Subjects draw up a questionnaire on defecation habits (frequency of defecation, amount and state of stool), and we collected fecal samples from the subjects both before entering and after ending the trial, to investigate LAB levels and inhibition of harmful enzyme activities. Results were tested with SAS and Student's t-test.Results: Analysis of questionnaire showed that there was an increase in the frequency of defecation and amount of stool excreted in defecation habit after LAB treatment, but there were no significant changes. And it also affects the intestinal environment, through significantly increase (p < 0.05) fecal LAB levels. In addition, tryptophanase and urease among harmful enzyme activities of intestinal microflora were significantly decreased (p < 0.05) after LAB treatment.Conclusion: LAB, when added to the standard treatment regimen for nursing home residents with chronic constipation, increased defecation habit such as frequency of defecation, amount and state of stool. So, it may be used as functional probiotics to improve human health by helping to prevent constipation.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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