A qualitative meta-analysis reveals consistent effects of atrazine on freshwater fish and amphibians.
Objective: The biological effects of the herbicide atrazine on freshwater vertebrates are highly controversial. In an effort to resolve the controversy, we conducted a qualitative meta-analysis on the effects of ecologically relevant atrazine concentrations on amphibian and fish survival, behavior,...
| Publicado en: | Environmental Health Perspectives Vol. 118; no. 1; pp. 20 - 33 |
|---|---|
| Autores principales: | , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
National Institute of Environmental Health Sciences
Jan2010
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105155888&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105155888 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00916765 3B5 jtl: Environmental Health Perspectives issn: 00916765 maglogo: N pubinfo: dt: Jan2010 vid: 118 iid: 1 pid: 56539 pub: National Institute of Environmental Health Sciences place: Research Triangle Park, North Carolina artinfo: ui: 105155888 2010605521 10.1289/ehp.0901164 NLM20056568 PMC2831963 105155888 ppf: 20 ppct: 13 formats: fmt: @attributes: type: P tig: atl: A qualitative meta-analysis reveals consistent effects of atrazine on freshwater fish and amphibians. aug: au: Rohr JR McCoy KA affil: Department of Integrative Biology, University of South Florida, Tampa, Florida 33620; jasonrohr@gmail.com sug: subj: Endocrine Glands Drug Effects Environmental Monitoring Herbicides Adverse Effects Marine Animals Reproduction Drug Effects Animal Studies Animals Funding Source Gonads Drug Effects Meta Analysis Sex Hormones Drug Effects Systematic Review ab: Objective: The biological effects of the herbicide atrazine on freshwater vertebrates are highly controversial. In an effort to resolve the controversy, we conducted a qualitative meta-analysis on the effects of ecologically relevant atrazine concentrations on amphibian and fish survival, behavior, metamorphic traits, infections, and immune, endocrine, and reproductive systems. Data sources: We used published, peer-reviewed research and applied strict quality criteria for inclusion of studies in the meta-analysis. Data synthesis: We found little evidence that atrazine consistently caused direct mortality of fish or amphibians, but we found evidence that it can have indirect and sublethal effects. The relationship between atrazine concentration and timing of amphibian metamorphosis was regularly nonmonotonic, indicating that atrazine can both accelerate and delay metamorphosis. Atrazine reduced size at or near metamorphosis in 15 of 17 studies and 14 of 14 species. Atrazine elevated amphibian and fish activity in 12 of 13 studies, reduced antipredator behaviors in 6 of 7 studies, and reduced olfactory abilities for fish but not for amphibians. Atrazine was associated with a reduction in 33 of 43 immune function end points and with an increase in 13 of 16 infection end points. Atrazine altered at least one aspect of gonadal morphology in 7 of 10 studies and consistently affected gonadal function, altering spermatogenesis in 2 of 2 studies and sex hormone concentrations in 6 of 7 studies. Atrazine did not affect vitellogenin in 5 studies and increased aromatase in only 1 of 6 studies. Effects of atrazine on fish and amphibian reproductive success, sex ratios, gene frequencies, populations, and communities remain uncertain. Conclusions: Although there is much left to learn about the effects of atrazine, we identified several consistent effects of atrazine that must be weighed against any of its benefits and the costs and benefits of alternatives to atrazine use. pubtype: Academic Journal doctype: meta analysis research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|