Analysis of classes used in the treatment of depression by physician-reported severity.

We analyzed use of therapeutic drug classes for the treatment of depression by the three levels of physician-reported disease severity (mild, moderate, and severe) to understand if the mix of therapeutic classes used to treat depression changes as disease severity increases. Prior to analyzing drug...

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Publicado en:Psychiatry (1550-5952) Vol. 7; no. 2; pp. 17 - 23
Autores principales: Lenderts S, Kalali AH, Weisler R
Formato: tables/charts Journal Article
Publicado: Matrix Medical Communications, LLC Feb2010
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Analysis of classes used in the treatment of depression by physician-reported severity.
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          Lenderts S
          Kalali AH
          Weisler R
        affil: Manager, Strategic Analytics, Quintiles Commercial, Falls Church, Virginia
      sug:
        subj:
          Antidepressive Agents Classification
          Antidepressive Agents Therapeutic Use
          Depression Classification
          Depression Drug Therapy
          Severity of Illness
          Antianxiety Agents, Benzodiazepine Therapeutic Use
          Antipsychotic Agents Therapeutic Use
          Prescribing Patterns Trends
          Serotonin Uptake Inhibitors Therapeutic Use
      ab: We analyzed use of therapeutic drug classes for the treatment of depression by the three levels of physician-reported disease severity (mild, moderate, and severe) to understand if the mix of therapeutic classes used to treat depression changes as disease severity increases. Prior to analyzing drug uses in each severity category, we established that in the 12 months ending November 2009, the majority of patients (65%) were assigned a severity rating of 'moderate' by their physician; 27 percent and eight percent of patients were designated as 'mild' and 'severe,' respectively. In general, we found that as disease severity changes, so too do the proportions of the various therapeutic classes used in depression. The differences in class mix by severity have persisted at least since the 12 months ending December 2008, and it appears that the mix of drug classes used in severe depression are becoming less similar to the class mix for moderate depression over time.
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    language: English
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